Citation: Vethaak AD, Baggelaar PK, van Lieverloo JHM and Ariese F (2016) Decadal Trends in Polycyclic Aromatic Hydrocarbon (PAH) Contamination Assessed by 1-Hydroxypyrene in Fish Bile Fluid in the Netherlands: Declining in Marine Waters but Still a Concern in Estuaries. Front. Mar. Sci. 3:215. doi: 10.3389/fmars.2016.00215 Decadal Trends in Polycyclic Aromatic Hydrocarbon (PAH) Contamination A...

BACKGROUND Polycyclic aromatic hydrocarbons (PAH) are environmental contaminants that pose significant risk to health of fish. Environmental pollution of fish is a topic of rising attention in Morocco. However, only few studies have been carried out so far, describing the potential threat of organic pollution to Moroccan aquatic ecosystem. Two polycyclic aromatic hydrocarbon (PAH) metabolites, ...

This research investigated the feasibility of using three strains Lactobacillus sp. viz. AM11, AM13, and AM14 previously isolated from dairy products to be used as probiotics in fish diet for phytase production. The bacteria grown in oxygenated media, bile salt, acid and supernatant of digestive tract  were examined for their antibiotic resistance and non-pathogenicity for using in fish feed. R...

Increased luminal bile acid hydrophobicity is associated with cytotoxicity and has been suggested to contribute to gut barrier dysfunction. The aim of this study was to compare 2 high-fat diets and a low-fat diet as to whether they modify fecal bile acid profile and hydrophobicity and/or susceptibility to dextran sodium sulfate (DSS) colitis in C57Bl/6J mice. Control and DSS-Control groups rece...

Most effluents from wastewater treatment works (WwTWs) contain estrogenic chemicals that include steroidal estrogens and xenoestrogens. We investigated the nature of mixtures of estrogenic contaminants taken up by two species of fish exposed to two WwTWs effluents. Sexually immature rainbow trout, Oncorhynchus mykiss, and sexually mature roach, Rutilus rutilus, were exposed to tap water, river ...

Bile salts present in gallbladder of wild and cultured red seabream, Pagrosomus major, a marine teleost were analyzed. The bile from wild red seabream was found to contain two previously unknown bile salts along with two known bile salts, taurocholate and taurochenodeoxycholate. Isolation of each bile salt was performed by column chromatography. Fast atom bombardment mass spectra of the unknown...

The gut-associated lymphoid tissue, connected with liver via bile and blood, constructs a local immune environment of both defense and tolerance. The gut-liver immunity has been well-studied in mammals, yet in fish remains largely unknown, even though enteritis as well as liver and gallbladder syndrome emerged as a limitation in aquaculture. In this study, we performed integrative bioinformatic...

Metabolism of benzo(a)pyrene (BaP) in vivo and in vitro was studied using two benthic fish species, English sole (Parophrys vetulus) and starry flounder (Platichthys stellatus), and Sprague-Dawley rats. At 24 h after administration of BaP (7.9 mumol/kg of body weight) to fish either p.o. (Experiment 1) or i.p. (Experiment 2), the specific activity of binding of BaP metabolites to hepatic DNA (p...

Recently we demonstrated that dietary fish oil (FO) causes changes in intrahepatic cholesterol transport and hypersecretion of cholesterol into bile in rats (J. Clin. Invest. 88: 943-951, 1991). We have now investigated in more detail the relationship between cholesterol and bile acid secretion in rats with chronic bile diversion fed purified diets supplemented (9% wt/wt) with either FO or corn...

This study demonstrated the effect of the simultaneous dietary administration of fish protein and fish oil, two macronutrients found in fish meat, on cholesterol metabolism in rats. Male Wistar rats were divided into four groups and fed an AIN-93G modified hypercholesterolmic diet with casein (20%) + soybean oil (7%), casein (10%) + fish protein (10%) + soybean oil (7%), casein (20%) + soybean ...