The emergent picture from the literature on the processing of self-related information suggests that in addition to the neural mechanisms involved in recognizing one's own face, there may also be neural representations of the self that are modality independent and favour the right hemisphere. We used focal, single-pulse transcranial magnetic stimulation in human subjects to assess cortical exci...

introduction: antibiotic supplements are regularly used in neuronal culture media to control contamination however, they can interfere with the neuronal excitability and affect electrophysiological properties. therefore, in this study, the effect of penicillin/streptomycin supplements on the spontaneous electrophysiological activity of hippocampal pyramidal neurons was examined. methods: electr...

Introduction: Antibiotic supplements are regularly used in neuronal culture media to control contamination however, they can interfere with the neuronal excitability and affect electrophysiological properties. Therefore, in this study, the effect of penicillin/streptomycin supplements on the spontaneous electrophysiological activity of hippocampal pyramidal neurons was examined. Methods: Electr...

　Introduction: Anodal transcranial direct current stimulation (a-tDCS) of the primary motor cortex (M1) has been shown to be effective in increasing corticomotor excitability. 　Methods: We investigated whether longer applications of a-tDCS coincide with greater increases in corticomotor excitability compared to shorter application of a-tDCS. Ten right-handed healthy participants received one se...

mechanoreceptors of foot sole likely contribute in the reflex regulations. stimulation of these receptors in the lateral aspect of the foot is corresponded to the lateral plantar division of the tibial nerve. therefore, it was hypothesized that repetitive low threshold afferents stimulation would have an inhibitory effect on the soleus h-reflexes. methods: sixteen normal subjects voluntarily pa...

the purpose of this study was to investigate the validity of the modified ashworth scale (mas) by using both the conventional (hmax/mmax ratio) and the new indicators (hslp/mslp) of motoneuron excitability. this research was a correlational study on twenty post-stroke patients. main outcome measures were the mas and electrophysiologic assessments. the latter was performed using both conventiona...

During past decades, the formation and storage principle of memory have received much attention in the neuroscience field. Although some studies have attempted to demonstrate the nature of the engram, elucidating the memory engram allocation mechanism was not possible because of the limitations of existing methods, which cannot specifically modulate the candidate neuronal population. Recently, ...

Anterior pituitary endocrine cells that release hormones such as growth hormone and prolactin are excitable fire action potentials. In these cells, several studies previously showed extracellular sodium (Na+) removal resulted in a negative shift of the resting membrane potential (RMP) subsequent inhibition spontaneous firing potentials, suggesting contribution Na+ background conductance. Here, ...

Cystic fibrosis transmembrane conductance regulator (CFTR), known as an epithelial Cl− channel, is increasingly noted to be expressed in the nervous system, although whether and how it plays a role neuronal excitability unclear. Given association of CFTR with fertility, we tested here possible involvement regulating hypothalamic neuron excitability. Patch-clamp Ca2+ imaging showed that pharmaco...

...................................................................................... 1 Acknowledgements ..................................................................... 4 Preface ........................................................................................ 5 Statement of Candidate Contribution ........................................... 6 Table of