Orientation of the cell division axis is essential for the correct development and maintenance of tissue morphology, both for symmetric cell divisions and for the asymmetric distribution of fate determinants during, for example, stem cell divisions. Oriented cell division depends on the positioning of the mitotic spindle relative to an axis of polarity. Recent studies have illuminated an expand...

In several migratory cells, the microtubule-organizing center (MTOC) is repositioned between the leading edge and nucleus, creating a polarized morphology. Although our understanding of polarization has progressed as a result of various scratch-wound and cell migration studies, variations in culture conditions required for such assays have prevented a unified understanding of the intricacies of...

Third-generation HF Automatic Link Establishment (ALE) achieves order-of-magnitude improvements over second-generation ALE in linking speed, network size, and traffic capacity. In this paper we examine the individual contributions to this performance by several of the techniques standardized in the third generation, including synchronous operation, dwell groups, and separate calling and traffic...

to study the effects of halopriming and hydropriming in overcoming salt and drought stress in corn (zea mays l.),two experiments were separately conducted at shahrood university of technology. seed treatments consisted ofcontrol (untreated seeds), soaking in distilled water for 32 h (hydropriming), and soaking in 50 mmol solution ofcacl2 for 16 h (halopriming). germination and early seedling gr...

common burnet (poterium sanguisorba) is a perennial herb from rose family (rosaceae) which is used to construct pastures. the studied plant can resist against freezing, cool and drought. the present study was conducted to study the seed germination parameters of common burnet in different thermal treatments as completely randomized design in 4 replications in 2013. treatments involved the effec...

Cortical pulling forces on astral microtubules are essential to position the spindle. These forces are generated by cortical dynein, a minus-end directed motor. Previously, another dynein regulator termed Spindly was proposed to regulate dynein-dependent spindle positioning. However, the mechanism of how Spindly regulates spindle positioning has remained elusive. Here, we find that the misalign...

Helper T cells discriminate among different antigen-presenting cells to provide their help in a selective fashion. The molecular mechanisms leading to this exquisite selectivity are still elusive. Here, we demonstrate that immunological synapses are dynamic and adaptable structures allowing T cells to communicate with multiple cells. We show that T cells can form simultaneous immunological syna...

Previous attempts to measure localization bias around a right-angle turn (L-trajectory) have found either no spatial bias off the trajectory (Whitney, Cavanagh, & Murakami, 2000) or a bias, in different experiments, both 'inside' and 'outside' the trajectory (Nieman, Sheth, & Shimojo, 2010). However, Eagleman and Sejnowski (2007) presented data showing that the perceived location of a brief fea...

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Mitotic spindle position is controlled by interactions of cortical molecular motors with astral microtubules. In animal cells, Partner of Inscuteable (Pins) acts at the cortex to coordinate the activity of Dynein and Kinesin-73 (Khc73; KIF13B in mammals) to orient the spindle. Though the two motors move in opposite directions, their synergistic activity is required for robust Pins-mediated spin...