625 IRAQ, Afghanistan, Kosovo, Bosnia, Somalia, Mozambique, Indonesia – all countries that have suffered or are currently suffering from the effects of conflict or natural disaster, and all countries where veterinary expertise has been required. While media images from such areas primarily focus on the human cost, livestock and draught animals are often an essential part of the lives of the peo...

1. Proof. (a) Let x ∈ [0, 1] and δ > 0, we want to show that there exist n such that nλ mod 1 ∈ (x−δ, x+δ), for which it suffices to show that there exists n0 and y ∈ (−δ, δ) such that n0λ ≡ y (mod 1). Then take n to be an appropriate multiple of n0. To prove the reduced proposition, choose m such that 10−m < δ. Note that there exist n1 < n2 such that (n1λ mod 1) and (n2λ mod 1) have the same f...

MicroRNAs (miRNAs) play a critical role in controlling tumor invasion and metastasis via regulating the expression of a variety of targets, which act as oncogenes or tumor suppressor genes. Abnormally expressed miR-625-3p has been observed in several types of human cancers. However, the molecular mechanisms of miR-625-3p-mediated tumorigenesis are largely elusive. Therefore, the aim of this stu...

Alloreactive CD8+ T-cells mediate the curative graft-versus-leukaemia effect, the anti-viral immunity and graft-versus-host-disease (GvHD) after allogeneic stem cell transplantation (SCT). Thus, immune reconstitution with CD8+ T-cells is critical for the outcome of patients after allogeneic SCT. Certain miRNAs such as miR-146a or miR-155 play an important role in the regulation of post-transpla...

Imprinted genes show differential expression between maternal and paternal alleles as a consequence of epigenetic modification that can result in ‘parent-of-origin’ effects on phenotypic traits1. There is increasing evidence from mouse and human studies that imprinted genes may influence behavior and cognitive functioning2. Previous work in girls with Turner syndrome (45,XO) has suggested that ...

The 2.05-Å resolution structure of the aquaglyceroporin from the malarial parasite Plasmodium falciparum (PfAQP), a protein important in the parasite’s life cycle, has been solved. The structure provides key evidence for the basis of water versus glycerol selectivity in aquaporin family members. Unlike its closest homolog of known structure, GlpF, the channel conducts both glycerol and water at...

OBJECTIVE To investigate the possible protective effect of recombinant human interleukin-11 (rhIL-11) against ifosfamide (IFS)-induced hemorrhagic cystitis (HC). MATERIALS AND METHODS Male Swiss mice (20-30g) were pretreated with rhIL-11 (25-625 mg, subcutaneously.) 30 min before intraperitoneal injection of IFS (400 mg/kg) or with saline (control group). Twelve hours later, HC was evaluated ...

context arthropod-borne diseases are remaining as a major public health issue in the resource-constrained settings. mosquitoes are closely associated with mankind since time immemorial and play an important role in the transmission of many dreadful diseases like malaria, filariasis, japanese encephalitis, dengue and yellow fever. over the decades, vector control is an important element to minim...