Electroporation is a phenomenon during which exposure of a cell to high voltage electric pulses results in a significant increase in its membrane permeability. Aside from the fact that after the electroporation the cell membrane becomes more permeable, the cells' geometrical and electrical properties change considerably. These changes enable use of the force on dielectric particles exposed to n...

We present measurements of the scaling of the dielectrophoresis force with electrode size and particle size, in order to determine the ultimate size limits for dielectrophoresis at the nanoscale. To demonstrate the feasibility of nano-manipulation we present studies on the dielectrophoretic manipulation of DNA with microfabricated electrodes using RF electric fields. We find that DNA undergoes ...

At neutral pH, DNA is a charged molecule. As such, it responds directly to an electric field, the phenomenon of electrophoresis. In contrast, the phenomenon of dielectrophoresis occurs when there is a dc or an ac electric field gradient. In that case, the development of nonuniform electric fields causes a force on any polarizable object, charged or neutral. The term dielectrophoresis was coined...

Ionic-based dielectrophoretic microchips have attracted significant attention due to their wide-ranging applications in electro kinetic and biological experiments. In this work, a numerical method is used to simulate the dynamic behaviors of ionic droplets in a microchannel under the effect of dielectrophoresis. When a discrete liquid dielectric is encompassed within a continuous fluid dielectr...

Single-walled carbon nanotubes (SWNTs) offer unique electrical and optical properties. Common synthesis processes yield SWNTs with large length polydispersity (several tens of nanometers up to centimeters) and heterogeneous electrical and optical properties. Applications often require suitable selection and purification. Dielectrophoresis is one manipulation method for separating SWNTs based on...

A concept of moving dielectrophoresis electrodes (MDEP) based on Microelectromechanical Systems (MEMS) actuators is introduced in this letter. An example design of tuneable dielectrophoresis filter is presented. Finite Element Analysis of the electrostatic field of the tuneable filter has been conducted. Results show that the trapping force can be adjusted by actuating the MEMS actuators. The p...

This paper describes the modeling and experimental verification of a castellated microelectrode array intended to handle biocells, based on common dielectrophoresis. The proposed microsystem was developed employing platinum electrodes deposited by lift-off, silicon micromachining, and photoresin patterning techniques. Having fabricated the microdevice it was tested employing Escherichia coli as...