Sir, I note with interest the recent report by Dr Menzies et al. of a patient with cranial diabetes insipidus secondary to arrested hydrocephalus.1 In his discussion he did not identify any previously reported cases of diabetes insipidus secondary to hydrocephalus. I recently reported a patient with diabetes insipidus which developed after subarachnoid haemorrhage.2 In the discussion, I noted a...

PURPOSE To describe the MR findings in the hypothalamic pituitary area in children with Langerhans cell histiocytosis and to define those MR alterations especially associated with the risk of developing diabetes insipidus. METHODS The hypothalamic-neurohypophyseal axis was studied by sagittal and coronal 1.5 T1-weighted MR imaging in 14 children with Langerhans cell histiocytosis (five with d...

Wolfram syndrome is the constellation of juvenile onset diabetes mellitus and optic atrophy, known as DIDMOAD (Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, and Deafness).Patients demonstrate diabetes mellitus followed by optic atrophy in the first decade, diabetes insipidus and sensorineural deafness in the second decade, dilated renal outflow tracts early in the third decade, and mult...

A patient with severe diabetes insipidus for 14 years was found to have an enlarged and eroded sella turcica with greatly reduced pituitary tissue on pneumoencephalography. It is suggested that the permanent diabetes insipidus may have resulted from growth of an intrasellar tumour, which subsequently infarcted spontaneously. Thyzoid and pituitary-adrenal function nevertheless remained good, whi...

Marquardt and Loriaux (I974) describe a kinship of two siblings with the combination of diabetes mellitus, diabetes insipidus, and optic atrophy in which there was additional evidence of renal tract dilatation, amino-aciduria, and neurosensory hearing deficit. These authors cite 41 cases of optic atrophy and diabetes mellitus reported since an association of these conditions was first described...

PURPOSE To investigate the value of MR in differentiating patients with primary polydipsia, who have an intact neurohypophyseal system, from those with central diabetes insipidus, who have impaired synthesis and/or release of vasopressin. METHODS Eighteen patients with clinically significant hypotonic polyuria were diagnosed endocrinologically as having primary polydipsia or diabetes insipidu...

Diabetes insipidus, characterized by excretion of copious volumes of dilute urine, can be life-threatening if not properly diagnosed and managed. It can be caused by two fundamentally different defects: inadequate or impaired secretion of antidiuretic hormone (ADH) from the posterior pituitary gland (neurogenic or central diabetes insipidus) or impaired or insufficient renal response to ADH (ne...

Diabetes is a term used to denote wide range of diseases. mellitus unites conditions quite different in pathogenesis, but the leading feature for them hyperglycemia and complications caused by it. Among non-endocrinologists, “diabetes”, which literally means flow water as if through siphon, mostly perceived precisely context carbohydrate metabolism disorders need hypoglycemic therapy. insipidus...

Abstract
 Diabetes insipidus is a poluuria polydipsia syndrome with hyperexcretion of hypotonic urine. It still rare in the world. Generally, diagnosed by dehydration and vasopressin test. was reported that woman experienced recurrent hypokalemia, cause unknown. After examination collected urine plasma osmolarity, it found diabetes waspresent. A test performed using intranasal desmopressin...

Clofibrate has been considered to be a relatively safe antidiuretic in the treatment of diabetes insipidus. However, we have recently had four cases of clofibrate-induced myopathy in patients with diabetes insipidus due to hypothalamic lesions. Physicians should therefore be aware of its occurrence and carefully monitor serum levels of CPK, GOT and GPT during the treatment of diabetes insipidus...