Zusammenfassung Die primäre Angiitis des Zentralnervensystems ist eine sehr seltene Erkrankung, welche durch entzündliche Infiltration der Gefäßwände von mittleren und kleinen Gefäßen ausschließlich im Zentralnervensystem, vorwiegend Gehirn, gekennzeichnet ist. Klinisch radiologisch kann sich die Erkrankung äußerst vielgestaltig präsentieren stellt daher besondere diagnostische Herausforderung ...

Cyclophosphamid has been widely used in patients with kidney diseases such as vasculitis, SLE, steroid-resistant nephrotic syndrome and also progressive IgA-nephropathy. Beside acute side effects like bone-marrow toxicity, infections, haemorrhagic cystitis, gastrointestinal side effects and hair loss, the main concern is the long-term effect of the drug which may occur years after treatment whe...

Background: Systemic lupus erythematosis (SLE) is a disorder with multiple organ involvement. Haematological abnormalities have been addressed in it, but acquired von Willebrand syndrome is a rarer phenomenon in current disease. The Case: We report acquired von Willebrand syndrome and SLE in a man with brown rash on face, gingival bleeding, easy bruising and epistaxis and laboratory finding of ...

OBJECTIVES Budd-Chiari syndrome is a rare and serious complication of Behçet's disease, and is the result of occlusion of the major hepatic veins, the adjacent inferior vena cava, or both. The aim of this study was to determine the prevalence, clinical and laboratory findings, and treatment and clinical course of Budd-Chiari syndrome associated with Behçet's disease. METHODS We analyzed retro...

Background: Although the chemotherapeutic agents have been known for their cytotoxic effects on normal mammalian cells, these compounds are used widely for controlling the carcinogenic cells proliferation. Cyclophosphamide (CP), a well-known nitrogen mustard alkylating agent is used for autoimmune disorders and tumors treatment. Considering the inhibitory effect of CP on cell division, the ovar...

Methods A male patient, who was 14 years old at that time, applied to the emergency department 4 years ago with right sided hemiplegia, right sided hemianopsia and disarticulated speech. Cranial MRI showed T2 and flair hyperintensities on optic tractus and chiasma opticum. This finding was consistent with either neoplastic diseases or aggressive inflamatory processes. Lomber punction revealed n...

nephritis remains an important problem in patients with systemic lupus erythematosus (sle). we conducted retrospective study to evaluate the efficiency of intravenous pulse cyclophosphamide in lupus nephritis: from 1983 to 1993, we reviewed 133 patients with biopsy proven lupus nephritis, 47 of them excluded because of short period of follow-up or defective laboratory data. eighty six patients ...