Polyamine conjugates with bicyclic terminal groups including quinazoline, naphthalene, quinoline, coumarine and indole have been obtained and their cytotoxic activity against PC-3, DU-145 and MCF-7 cell lines was evaluated in vitro. Their antiproliferative potential differed markedly and depended on both their chemical structure and the type of cancer cell line. Noncovalent DNA-binding properti...

Platinum diimine bis(alkynyl), bis(thiolate) or bis(alkoxolate) complexes (diimine)Pt(XR)2 (XR=C CR, OR, SR) constitute a prominent class of photosensitizers with numerous applications in the fields of photocatalysis and light to (chemical) energy conversion; e.g., photocatalysed hydrogen production. The photoreactive state is usually accessed by excitation into the (RX)2Pt-diimine charge-trans...

lycium species is a popular medicinal plant in the traditional chinese medicine and lycium ruthenicum is a native medicinal plant of iran. lycium genus has several biologically important properties too. investigation of chemical composition of ethyl acetate extract of this plant is the goal of this study. two coumarins (scopoletin and sculetin) and methyl-2-hydroxy-4-undecanoxy-trans-cinamate w...

A new series of aromatic and heterocyclic sulfonamides, including six new derivatives, 2-(3-cyclohexene-1-carbamido)-1,3,4-thiadiazole-5-sulfonamide (CCTS), 4-(3-cyclohexene-1-carbamido) methyl-benzenesulfonamide (CCBS), 2-(9-octadecenoylamido)-1,3,4-thiadiazole-5-sulfonamide (ODTS), 2-(4,7,10-trioxa-tetradecanoylamido)-1,3,4-thiadiazole-5-sulfonamide (TDTS), 2-(coumarine-3-carbamido)-1,3,4-thi...

We show an experimental and computational comparison between the resolution power, the contrast and the focal depth of a nonlinearly propagated diffraction-free beam and of other beams (a linear and a nonlinearly propagated Gaussian pulse): launching a nondiffractive Bessel pulse in a solution of Coumarine 120 in methanol creates a high contrast, 40 mm long, 10 microm width fluorescence channel...