نتایج جستجو برای: copper sulfateseizurepentylenetetrazole valproic acid

تعداد نتایج: 821568  

Journal: :مجله علوم اعصاب شفای خاتم 0
marzieh darvishi a. shefa neuroscience research center, khatam alanbia hospital, tehran, iran. b. department of anatomy, tarbiat modares university, tehran, iran. taghi tiraihi a. shefa neuroscience research center, khatam alanbia hospital, tehran, iran. b. department of anatomy, tarbiat modares university, tehran, iran. taher taheri shefa neuroscience research center, khatam alanbia hospital, tehran, iran.

spinal cord injury (sci), a common result of car accidents, high-altitude falls and crashes, and other violent injuries is increasing yearly. histone deacetylases (hdac) inhibitors including depakine the main characteristics of the use of anti-inflammatory. the purpose of this investigation is to evaluate the effect of depakine intervention on the acute sci at the chronic phase using functional...

Journal: :American journal of clinical pathology 1994
A Dasgupta M Jacques

Limited studies indicate increased free fraction of valproic acid in uremia. One study also described displacement of valproic acid from protein binding by salicylate in children with epilepsy. The authors studied in vitro interaction of valproic acid and salicylate in uremic sera and compared their results with same interactions in normal sera. As expected, the concentrations of free valproic ...

Journal: :Journal of the Medical Association of Thailand = Chotmaihet thangphaet 2012
Wichai Suntimaleeworakul Suthiporn Patharachayakul Sarunyou Chusri

Valproic acid and meropenam is commonly co-administrated in neurosurgical patients. Meropenem potentially decreases the valproic acid level, which may cause perioperative seizure. There has been no previous report of drug interaction between valproic acid and meropenem in Thailand. The authors report a patient who faced uncontrolled seizure after co-administrated valproic acid and meropenem. Th...

بیگلری, علیرضا, عبدانی پور, علیرضا, مردی, علی, نجات بخش, رضا,

Background and Objective: Spinal cord injury (SCI) leads to the loss of axons and cell death via necrosis and apoptosis, eventually resulting in sensory and motor dysfunction. The aim of this study was to evaluate the effects of valproic acid on the inhibition of apoptosis and the improvement of motor function in the rat model of spinal cord injury. Materials and Methods: Contusion model was u...

Journal: :The Annals of pharmacotherapy 2000
S L Kane M Constantiner A E Staubus C D Meinecke J R Sedor

OBJECTIVE To report a case of valproic acid overdose treated successfully with high-flux hemodialysis without the addition of charcoal hemoperfusion. CASE SUMMARY A 25-year-old white woman with a history of multiple suicide attempts and schizophrenia presented after ingesting an unknown amount of valproic acid. She became comatose and developed hypotension and lactic acidosis as valproic acid...

2009
Andrea Domenico Praticò Piero Pavone Maria Grazia Scuderi Giovanni Li Volti Renato Bernardini Giuseppina Cantarella Lorenzo Pavone

INTRODUCTION An epileptic child had been long treated with valproic acid and lamotrigine. After a few years of treatment, he manifested severe clinical signs of hypocalcemia. We retain that valproic acid could have caused such metabolic dysfunction. CASE PRESENTATION We report here the involvement of valproic acid in symptomatic hypocalcemia in an 11-year-old epileptic white patient in treatm...

Journal: :The Netherlands journal of medicine 2011
M C Prins J J van Meijel

A patient with valproic acid induced hyperammonaemic encephalopathy is presented. During chronic treatment with valproic acid this patient developed a potentially life-threatening encephalopathy without signs of liver failure. After discontinuing the valproic acid the patient recovered completely. In the case of a patient presenting with hyperammonaemic encephalopathy, the possibility of the us...

Journal: :International journal of pharmaceutics 2000
N Utoguchi K L Audus

The biochemical mechanisms mediating the rapid distribution of valproic acid across placenta are not precisely known. We have characterized valproic acid transport by the human trophoblast using the human choriocarcinoma cell line, BeWo. The uptake of [14C]valproic acid by BeWo cells was found to be saturable and blocked by pre-exposure to the metabolic inhibitors, sodium azide and 2,4-dinitrop...

Journal: :Hong Kong medical journal = Xianggang yi xue za zhi 2001
C H Ko C K Kong P W Tse

OBJECTIVE To investigate the relationship between platelet count and serum valproic acid level, age, duration of valproic acid therapy, and polytherapy, and to determine the clinical significance of thrombocytopenia associated with high-dosage valproic acid therapy. DESIGN Cross-sectional study. SETTING Residential unit for neurologically impaired children and paediatric out-patient clinic,...

Journal: :Pharmacopsychiatry 2007
R Yoshimura K Shinkai N Ueda J Nakamura

OBJECTIVE To investigate the effect of valproic acid on plasma levels of risperidone and its active metabolite, 9-hydroxyrisperidone under steady state conditions in 12 schizophrenic patients. METHODS The efficacy and tolerability for the combination treatment of valproic acid and risperidone were examined. RESULTS The addition of valproic acid to risperidone significantly reduced total sco...

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