Are acquired characteristics inherited? We admit that individuals inherit a certain constitution, and that definite variations from this constitution are acquired during life-time, according to well-known laws. The question is: Are these definite acquired variations in any degree transmitted, or are the congenital variations in the constitution of the offspring independent of those which have b...

An accessory coronary cusp in aortic valve is a rare congenital cardiovascular malformation with an estimated incidence of 0.003 to 0.043% of all congenital heart disease. It is also describe as a quadricuspid aortic valve (QAV). Several different anatomical variations of quadricuspid aortic valve have been described. Current technology enables noninvasive diagnosis in most cases. Here we repor...

Heterotaxy syndrome or situs ambiguous is a rare congenital disease in which the pattern of anatomical organization of the thoraco-abdominal visceral and vascular structures is not arranged in normal position. Patients with heterotaxy syndrome represent a wide range of anatomical variations including thoraco-abdominal structures. Here we report a rare case of asymptomatic heterotaxy syndrome in...

Congenital anomalies and within them anatomical variations of coronary arteries, although uncommon, are being increasingly studied diagnosed due to the close relationship symptoms such as angina, dyspnea, syncope or arrhythmias in young people without comorbidities. This study aimed present case report a patient with ischemic secondary malformation artery. We describe moment admission, diagnosi...

conclusions we explain embryologic origin, differential diagnosis, other associated anomalies and its treatment by reviewing literature. introduction midline cleft of mandible, classified as tessier 30 clefts is extremely rare, with less than 100 reported cases in the latest studies. variations in severity and associated malformations have been reported before. case presentation in this report,...

OBJECTIVE To determine the relative contributions of mutations in congenital cataract cases in an Indian population by systematic screening of genes associated with cataract. METHODS We enrolled 100 congenital cataract cases presenting at the Dr. R. P. Centre for Ophthalmic Sciences, a tertiary research and referral hospital (AIIMS, New Delhi, India). Crystallin, alpha A (CRYAA), CRYAB, CRYGs...

It is important to investigate the incidence of congenital color deficiency and to determine the type and degree because the color deficiency can effect as a handicap to certain occupations. The incidence of congenital color deficiency is remarkably constant among Caucasians but other races show considerable variations. We investigated the incidence of congenital color deficiency among Koreans ...