نتایج جستجو برای: cns tumor
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Background: Tumors of the central nervous system (CNS) are a heterogeneous group of neoplasms with different prevalence in different sex and age groups and various parts of CNS. Objectives: Determining the relative frequency of different types of CNS tumors in different ages, sex and CNS anatomical locations. Materials and Methods: This retrospective study was performed using pathological repor...
Introduction: Meningioma is the most frequent primary tumor in central nervous system (CNS), representing 33.8% of all intracranial tumors. Breast cancer (BC) among women, 25.2% malignancies females.
Central neurocytoma (CN) is a rare and elusive tumor. The relationship between clinical outcome, tumor nature, treatment of CN remains controversial. There were eight patients in our hospital from 2014 to 2021, the prevalence accounted for 0.36% brain tumors. All them underwent surgical removal, two combined with adjuvant radiotherapy (RT). We found that four without complications had small tum...
• STI1 is a co-chaperone involved in the correct client proteins' folding. Extracellular crucial for CNS maintenance and homeostasis. expression associated with tumor progression impaired survival of patients. can be biomarker therapeutic target several malignancies. Stress inducible protein 1 (STI1) acting Hsp70 Hsp90 proteins’ folding therefore cellular Besides being expressed cytosol, also f...
Primary central nervous system lymphoma (PCNSL) is a rare cancer that confined to the brain, spinal cord, leptomeninges and eyes. The origin of this type of lymphoma is often type B lymphocytes, and because the central nervous system (CNS) has no lymph nodes or lymphatic vessels, the cause of PCNSL is still uncertain (1). But its source appears to be from lymphocytes located in the CNS (2). Thi...
Primary dural lymphoma (PDL) is a subtype of primary central nervous system (CNS) (PCNSL) with only an extra-axial location. It accounts for less than 1% all CNS lymphomas. PDL sporadic tumor, and in the preoperative period, because imaging characteristics, it usually mimicking meningioma. Usually, low-grade B-cell relatively good response to surgical resection or without radiotherapy. Here we ...
Wilm's tumor is the 4th common malignant tumor of childhood (after CNS tumors, Non Hodgkin's lymphoma and neuroblastoma), and indeed comprises about 5% of childhood malignancies. This is a retrospective study of histologic findings of 23 cases of wilm ' s tumor referred to Mofid Children's Hospital from 1991-1995. 20 Cases were classified as favorable and 3 cases as unfavorable histology . Corr...
Deciding to use an organ from a donor with a primary central nervous system (CNS) tumor necessitates offsetting the risk of tumor transmission with the chances of survival if the patient waits for another offer of a transplant. Published data vary in the quoted risk of tumor transmission. We used data obtained by reviewing 246 UK recipients of organs taken from donors with CNS tumors and found ...
Central nervous system tumors are marked with high intra-and inter-tumoral heterogeneity. For instance, an integrative large scale gene expression study performed in 2010 revealed 4 subtypes glioblastoma multiforme (GBM) with differential responses to treatment and prognosis [1]. A more comprehensive GBM classification based on combination of epigenetics, copy number variation, gene expression ...
PURPOSE Cancer spread to the central nervous system (CNS) often is diagnosed late and is unresponsive to therapy. Mechanisms of tumor dissemination and evolution within the CNS are largely unknown because of limited access to tumor tissue. MATERIALS AND METHODS We sequenced 341 cancer-associated genes in cell-free DNA from cerebrospinal fluid (CSF) obtained through routine lumbar puncture in ...
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