نتایج جستجو برای: cineole

تعداد نتایج: 853  

Journal: :Bioorganic & medicinal chemistry letters 2013
Hee-jin Jun Minh-Hien Hoang Siok-Koon Yeo Yaoyao Jia Sung-Joon Lee

We investigated the effect of cineole on the expression of genes related to reverse cholesterol transport and hepatic fatty acid metabolism. Cineole, a small aroma compound in teas and herbs, significantly stimulated the transactivation of liver X receptor modulator (LXR)-α and LXR-β. The mRNA and protein expression of LXRs and their target genes, including ABCA1 and ABCG1, was significantly in...

2017
Asli Celebioglu Zehra Irem Yildiz Tamer Uyar

The electrospinning of self-standing nanofibrous webs from inclusion complexes (IC) of cineole and p-cymene with two modified cyclodextrins (HPbCD, HPcCD) was achieved without using carrier polymeric matrix. Although they are highly volatile, certain amount of cineole and p-cymene was protected in cyclodextrin inclusion complexes nanofibers (CD-IC-NF). That is, 68.4%, 78.1%, 54.5% and 44.0% (w/...

Journal: :The Journal of pharmacy and pharmacology 2001
F A Santos R M Silva A R Tomé V S Rao M M Pompeu M J Teixeira L A De Freitas V L De Souza

The effects of 1,8-cineole on D-galactosamine/lipopolysaccharide (GalN/LPS)-induced shock model of liver injury was investigated in mice. The co-administration of GalN (700 mg kg(-1), i.p.) and LPS (5 microg kg(-1), i.p.) greatly elevated serum concentrations of tumour necrosis factor-alpha (TNF-alpha), alanine aminotransferase and aspartate aminotransferase, and induced massive hepatic necrosi...

Journal: :BMB reports 2012
Kyung-Hyun Cho

We recently reported that a water extract of laurel or turmeric, 1,8-cineole enriched fractions, showed hypolipidemic activity in the zebrafish model. Therefore, the present study investigated the cineole's anti-oxidant and anti-inflammatory activities in lipoprotein metabolism in vitro and in vivo. Cineole had inhibitory effects on cupric ion-mediated oxidation of lipoproteins in general, whil...

Journal: :Microbiology 2014
Jared Nigg Gary Strobel W Berk Knighton Jonathan Hilmer Brad Geary Syed Riyaz-Ul-Hassan James K Harper Domenic Valenti Yuemin Wang

A Nodulisporium species (designated Ti-13) was isolated as an endophyte from Cassia fistula. The fungus produces a spectrum of volatile organic compounds (VOCs) that includes ethanol, acetaldehyde and 1,8-cineole as major components. Initial observations of the fungal isolate suggested that reversible attenuation of the organism via removal from the host and successive transfers in pure culture...

Journal: :Scientific reports 2015
Jun-Hyung Tak Murray B Isman

Synergistic interactions between constituents of essential oils have been reported for several areas of research. In the present study, mechanisms that could explain the synergistic action of the two major insecticidal constituents of rosemary oil, 1,8-cineole and camphor against the cabbage looper, Trichoplusia ni were investigated. 1,8-Cineole was more toxic than camphor when applied topicall...

2014
Ka Young Kim Hyo Jin Seo Sun Seek Min Mira Park Geun Hee Seol

The aim of this study was to investigate the effect of inhalation of eucalyptus oil and its constituents on anxiety in patients before selective nerve root block (SNRB). This study was a randomized controlled trial carried out in 62 patients before SNRB. The patients were randomized to inhale limonene, 1,8-cineole, or eucalyptus oil, each at concentrations of 1% vol/vol in almond oil or almond ...

2012
Masayuki Takaishi Fumitaka Fujita Kunitoshi Uchida Satoshi Yamamoto Maki Sawada (Shimizu) Chihiro Hatai (Uotsu) Mayumi Shimizu Makoto Tominaga

BACKGROUND Essential oils are often used in alternative medicine as analgesic and anti-inflammatory remedies. However, the specific compounds that confer the effects of essential oils and the molecular mechanisms are largely unknown. TRPM8 is a thermosensitive receptor that detects cool temperatures and menthol whereas TRPA1 is a sensor of noxious cold. Ideally, an effective analgesic compound ...

Journal: :The Journal of antimicrobial chemotherapy 2009
E R Hendry T Worthington B R Conway P A Lambert

OBJECTIVES Effective disinfection and antisepsis is pivotal in preventing infections within the healthcare setting. Chlorhexidine digluconate (CHG) is a widely used disinfectant/antiseptic possessing broad-spectrum antimicrobial activity; however, its penetration into bacterial biofilms and human skin is poor. The aim of this study was to investigate the antimicrobial efficacy of crude eucalypt...

2013
Juergen Fischer Uwe Dethlefsen

OBJECTIVE Cineole has mucolytic, bronchodilating and anti-inflammatory properties and reduces the exacerbation rate in patients suffering from COPD, as well as ameliorates symptoms in patients suffering from asthma and rhinosinusitis. Based on these effects, we therefore postulated the hypothesis that patients with acute bronchitis would also benefit from therapy with Cineole. METHODS As part...

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