background: schizophrenia is a devastating psychiatric disorder and its  positive and negative symptoms have negative effects on social functions. a combination of pharmacological and non-pharmacological treatments is considered more effective for this condition. the present study aimed to determine the effect of a group horticulture program on psychiatric symptoms in patients with chronic schi...

Background: Many studies in the 20th century have reported an association between Schizophrenia and Catatonia. Structural brain abnormalities also been found many psychotic illnesses, including schizophrenia there are findings of large ventricles with chronic deteriorating psychosis. It is possible that a ventricular system may increase likelihood catatonia course. Cavum Septum Pellucidum (CSP)...

schizophrenia is a chronic psychotic disorder with unknown etiology that causes cognitive impairment, affecting thinking, behavior, social function, sleep and dream content. this study considered the dream content of patients with schizophrenia, siblings of patients with schizophrenia, patients with psychiatric diagnoses other than schizophrenia, and a group of healthy controls. the aim of this...

anxiety is one of the symptoms in chronic schizophrenic patients. past research studies show that psychodrama as a group therapy is effective in treatment and rehabilitation of psychological disorders. the aim of this study is to explore the effect of psychodrama on the reduction of anxiety in schizophrenic patients. 26 male hospitalized chronic schizophrenic patients were randomly assigned int...

OBJECTIVE The authors sought to map gray matter changes in first-episode schizophrenia and to compare these with the changes in chronic schizophrenia. They postulated that the data would show a progression of changes from hippocampal deficits in first-episode schizophrenia to include volume reductions in the amygdala and cortical gray matter in chronic schizophrenia. METHOD A systematic searc...

selective estrogen receptor modulators (serms) such as raloxifene have already shown beneficial effects on negative, positive and general psychopathology symptoms in postmenopausal women with schizophrenia. the purpose of the present investigation was to assess the efficacy of raloxifene as an adjuvant agent in the treatment of men with chronic schizophrenia in an 8-week double-blind and placeb...

Schizophrenia is a chronic debilitating mental illness. In many aspects, the neuropathology of schizophrenia closely associated with neuroinflammation, especially microglial activation. Microglial hyperactivity, which characterized by predominant release proinflammatory cytokines serves as basis neuroinflammation hypothesis in schizophrenia. The enhanced inflammatory induce neuronal susceptibil...

As a chronic psychiatric disorder, schizophrenia affects the worldwide population with a lifetime prevalence of 1% and considerable long-term mortality, morbidity, and burden. Besides the adverse effects of routine treatment regimens, a significant portion of patients remain symptomatic despite treatment, especially those with negative symptoms which are the major disabling factors in these pat...