background: the purpose of this study was to test the hypothesis that the addition of buspirone, a partial agonist of 5ht1a receptor, to ongoing treatment with typical antipsychotics would improve the positive and negative symptoms in patients with chronic schizophrenia. materials and methods: in this study, 50 patients including 40 male and 10 female were recruited with chronic schizophrenia w...

objectives: psychotropic drug use in the elderly with chronic schizophrenia is an important issue in the field of psychiatry. the main goal of this study was to clarify the pattern of such drug use in these patients, in order to consider such therapy plan and focus on its cost attributing measures, for a more reasonable quality of care program. methods: in this descriptive study, participants i...

introduction: patients with schizophrenia characteristically exhibit cognitive deficits. the level of cognitive impairment is found to predict the functional outcome of the illness more strongly than the severity of positive or negative symptoms. the purpose of this study was to assess the efficacy of ondansetron, a 5-ht3 receptor antagonist as an adjuvant agent in the treatment of chronic schi...

Introduction: Patients with schizophrenia characteristically exhibit cognitive deficits. The level of cognitive impairment is found to predict the functional outcome of the illness more strongly than the severity of positive or negative symptoms. The purpose of this study was to assess the efficacy of ondansetron, a 5-HT3 receptor antagonist as an adjuvant agent in the treatment of chronic...

background : schizophrenia is a serious, chronic, and often debilitating neuropsychiatric disor­der. its causes are still poorly understood. besides genetic and non-genetic (environmental) fac­tors are thought to be important as the cause of the structural and functional deficits that character­ize schizophrenia. this study aimed to compare toxoplasma gondii infection between schizo­phrenia pat...

Objectives: Patients with schizophrenia are characterized with deficiencies in various aspects of social functioning. Given the relationship between social functioning deficits and relapse in these patients, identification of underlying factors is of significant importance. Thus, in this study, the contribution of each dimension of social cognition (Emotion Perception [EP], Theory of Mind [ToM]...

Persons with schizophrenia have higher rates of cardiovascular disease and exhibit inflammatory abnormalities. Emerging evidence has linked the gut microbiome changes to schizophrenia. However, there been limited research into functional pathways by which microbiota contributes phenotype persons chronic

Background: Schizophrenia is a devastating psychiatric disorder and its  Positive and negative symptoms have negative effects on social functions. A combination of pharmacological and non-pharmacological treatments is considered more effective for this condition. The present study aimed to determine the effect of a group horticulture program on psychiatric symptoms in patients with chronic...