نتایج جستجو برای: choroid
تعداد نتایج: 6564 فیلتر نتایج به سال:
The choroid plexus produces cerebrospinal fluid and plays an important role in brain homeostasis both pre and postnatally. In vitro studies have suggested that cells from adult choroid plexus have stem/progenitor cell-like properties. Our initial aim was to investigate whether such a cell population is present in vivo during development of the choroid plexus, focusing mainly on the chick choroi...
A sheet of choroid plexus epithelial cells extends into each cerebral ventricle and secretes signaling factors into the CSF. To evaluate whether differences in the CSF proteome across ventricles arise, in part, from regional differences in choroid plexus gene expression, we defined the transcriptome of lateral ventricle (telencephalic) versus fourth ventricle (hindbrain) choroid plexus. We find...
OBJECT Malignant progression of choroid plexus papillomas has been occasionally reported, but this issue has not yet been systematically addressed. METHODS Frequency and extent of malignant progression were examined in a retrospective series of 124 primary choroid plexus papillomas using uniform histological criteria. RESULTS After gross-total resection and a mean follow-up period of 59 mon...
1. Abstract 2. Introduction 3. Structure and Functions of Choroid Plexus 3.1. Structure of choroid plexus 3.2. Functions of choroid plexus 3.3. Composition of cerebrospinal fluid 4. Ageing of Choroid Plexus 4.1. Anatomical modifications in ageing 4.2. Functional alterations in ageing 4.3. Modification of cerebrospinal fluid in ageing 5. Choroid Plexus and Alzheimer’s Disease 5.1. Anatomical alt...
Uveal melanoma (UM) is the most frequent intraocular malignancy in adults, affecting iris, choroid, and ciliary bodies [...]
The choroid plexus is an important central nervous system (CNS) structure that is often neglected in pathologic and radiologic studies of intracranial diseases. The choroid plexus may serve as 1) a portal of entry for pathogens into the CNS, 2) a target for various systemic disorders, 3) a reflector of various diseases that affect the brain and meninges, or 4) a site of primary processes such a...
Background: The most common mechanism associated with the development of choroid plexus carcinoma seems to be mutation of the TP53 gene. The R337H mutation of the TP53 gene has been reported in a significant proportion of patients with choroid plexus tumors. The aim of the present study was to use immunohistochemical techniques to establish whether the presence of the R337H mutation is associat...
Although heavy metal ions are known to be toxic to the central nervous system (CNS), the mechanisms by which the CNS may protect itself from initial challenges of such toxic ions is unknown. The choroid plexus is the principal site of formation of the cerebrospinal fluid (CSF) which bathes the brain. We have determined in rats and rabbits that after intraperitoneal administration of lead, cadmi...
Choroid plexus papilloma is a rare benign tumor accounting for 0.5% of all intracranial tumors. The majority of choroid plexus papillomas occur during the first 2 years of life in the ventricular system. Moreover, dense calcification of the tumor is uncommon. We report an adult case of densely calcified, atypical choroid plexus papilloma that originated from the cerebellopontine angle without c...
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