Background: One important reproductive characteristic of Mammals is the production of milk to nurse the neonate. In order to better understand the evolution of milk we have investigated gene expression in milk cells from monotremes which are the most ancient representative of the mammalian lineage. Materials and Methods: Using a milk cell cDNA sequencing approach we characterise milk protein se...

Caseins, which are contained in milk, play a significant role the development of clinical symptoms allergic reactions adults and children. To date, properties caseins have been studied, their primary structure has identified. However, despite available scientific reviews original articles, an issue structural organization milk casein micelles biological functions is still very controversial. In...

Angiotensin-converting enzyme (ACE) plays a central role in blood pressure regulation by producing the vasoconstrictor angiotensin II. The inhibition of ACE with natural inhibitors, as alternatives to avoid the side effect of synthetic drugs, is a major target in the prevention of hypertension. In this study, we examined the separated caseins and whey proteins of goat milk for the presence of A...

BOVINE MILK POSSESSES A PROTEIN SYSTEM CONSTITUTED BY TWO MAJOR FAMILIES OF PROTEINS: caseins (insoluble) and whey proteins (soluble). Caseins ( α S1, α S2, β , and κ ) are the predominant phosphoproteins in the milk of ruminants, accounting for about 80% of total protein, while the whey proteins, representing approximately 20% of milk protein fraction, include β -lactoglobulin, α -lactalbumin,...

Of all food proteins, bovine milk proteins are probably the most well characterized chemically, physically, and genetically. The primary structures are known for most genetic variants of a s l , as2-, 0-. and K-caseins, &lactoglobulin, and a-lactalbumin. Secondary and tertiary structures of the whey proteins have been determined, and secondary structures of the caseins have been predicted from ...

In this study, protein and salt distributions in the milk of 48 Holstein-Friesian cows were studied. Gross composition samples variation between individual was line with expectation. However, mineralisation casein fraction, expressed mmol protein-associated calcium per 10 g casein, differed >2-fold samples. Reasons for are unknown could not be correlated to and/or genetic variants caseins. Furt...

Caseins were separated from whey proteins by acid precipitation of skimmed rabbit milk. Whole casein was resolved by sodium dodecyl sulphate/polyacrylamide-gel electrophoresis into three major bands with apparent relative molecular masses (Mr of 31 000, 29 000 and 25 000. On agarose/urea-gel electrophoresis whole casein gave three bands with electrophoretic mobilities a, , and y. The three comp...

Caseins are members of a class of proteins with extremely open and flexible conformations. Here, we consider what features of their sequences are important in maintaining such a structure. Primary structures of the as,-, 8and Kcaseins from species including the cow, sheep, rat, mouse, rabbit and guinea pig were aligned both by a variety of automatic multiple alignment procedures, and manually, ...

1. An improved method for the preparation of phosphoprotein phosphatase from ox spleen is described. The enzyme was purified 60-fold with a yield of 21 %. 2. The enzyme preparation was free from proteolytic activity and had no action on fl-glycerol phosphate. 3. The enzyme was active on caseins, phenyl phosphate and inorganic pyrophosphate. Hence it cannot be described as a specific phosphoprot...