Calcium phosphates are the main inorganic components of bone and tooth tissues. The nucleation of calcium phosphates is thought to proceed by aggregation of so called prenucleation clusters (PNCs), which are already present in body fluids before nucleation. This nucleation pathway cannot be fitted in the frame of the Classical Nucleation Theory. We investigated the structure and verified the st...

The formation of calcium phosphate phases is extremely important in a biomedical engineering context. These phosphates are used in many applications, such as grafts, drug-delivery processes and evaluation of the bioactivity of metallic surfaces. Considering this scenario, it is useful to evaluate the thermodynamic conditions for the precipitation of phosphates of biomedical interest, mainly hyd...

Thermodynamics of the precipitation calcium phosphates shows importance pH and order introduction precursor ions on textural (morphology, surface area) structural (defects) properties hydroxyapatites.

Clinoptilolite zeolite was chemically modified with sodium, calcium, or magnesium to comparatively study the physical recovery of ammonium and phosphates from simulated blackwater.

We investigated the contribution of external calcium ions to inositol phosphate-induced exocytosis in sea urchin eggs. We show that: (a) inositol phosphates activate eggs of the sea urchin species Lytechinus pictus and Lytechinus variegatus independently of external calcium ions; (b) the magnitude and duration of the inositol phosphate induced calcium changes are independent of external calcium...

Inositol phosphates function as second messengers for a variety of extracellular signals. Ins(1,4,5)P(3) generated by phospholipase C-mediated hydrolysis of phosphatidylinositol bisphosphate, triggers numerous cellular processes by regulating calcium release from internal stores. The Ins(1,4,5)P(3) signal is coupled to a complex metabolic cascade involving a series of phosphatases and kinases. ...

Bioactive composites that enable the formation of calcium phosphates have received increased attention over the last decade, in the development of osteoconductive biomaterials for orthopaedic applications. In this work, tripolyphosphate (TPP)-cross-linked chitosan/gelatin composites (TPP-CG) were prepared for the growth of shape- and size-controlled calcium phosphates on/in the composites. The ...