peripheral blood stem cell transplantation (pbsct) is an effective treatment for hematological malignancies. mobilization of peripheral blood progenitor cells performs in different ways among transplantation centers. forceful mobilization schedules are comprised of growth factor alone, chemotherapy along with growth factor and also, a newly combination of novel agent such as plerixafor with any...

conclusions according to the results of this study, effect of biochemical interfering factors on test results of impedance cell counter must be considered in clinical laboratories. results comparison between case and control groups revealed that uremia caused significant increase in mcv and rdw levels (p < 0.05) and had no effect on mch level (p > 0.05). both hyperglycemia and hyperlipemia caus...

background: asphyxia is a common cause of perinatal mortality in 5-10% of all births worldwide. the present parameters for determining perinatal asphyxia, e.g. preeclampsia, cannot be considered as markers per se, and require auxiliary markers, e.g. increased number of nucleated red blood (nrbc) cells, for early diagnosis of perinatal asphyxia. objective: in this study, we evaluated the mean nr...

results there were no significant differences between the 4 groups in white blood cell count, hemoglobin, hematocrit, and esr at baseline (p > 0.05). the number of platelet units was remarkably higher, but the number of mpv and hco3 was considerably lower in patients with loss/ failure criteria. conclusions mpv is higher in the case of platelets destruction, and this is commonly observed in inf...

from 1996 to 2002, fifty three patients with major beta-thalassemia received allogeneic peripheral blood stem cell trans plantation (pbsct). median age was 6 years .twenty two were class i, 17 class ii and 14 class iii. all of the donors were hla-identical. conditioning regimen for class i and ii patients consisted of cyclophosphamide (cy) 50 mg/kg/day for 4 days + busulfan (bu) 3.5 mg/kg for 4...

cell based therapeutics is one of the most rapidly advancing medical fields, bringing together a range of fields including transplantation, tissue engineering and regeneration, biomaterials and stem cell biology. however, traditional cell-based therapeutics have many limitations, one of which is their harmful effects exhibited on healthy body cells due to their lack of specificity. nanomedicine...

background: gallium-66 (t1/2= 9.49 h) is an interesting radionuclide that has potential for positron emission tomography (pet) imaging of biological processes in intermediate to slow target tissue uptake. oxine has been labeled with this radioisotope in the form of [66ga]gallium chloride for its possible diagnostic properties. materials and methods: 66ga was produced in the 30 mev cyclotron (cy...

  SUMMARY Growth factors or colony stimulating factors (CSFs)recently became the subject of headlines around the world. Many published articles in the last few years indicate that the CSFs can correct anemia and pancytopenia of the great majority of patients. Recombinant CSFs are available to the many scientific and therapeutic centers in the U.S.A, Europe and Japan these days. Erythrop oieti...

background &amp; objective: there are many common infections and inflammations among people over the world. this demands an affordable and reliable test with high sensitivity/specificity to predict or confirm the diagnosis of such cases in routinely clinical practice. in the present study, we aimed to find any potential correlation between serum levels of ggt and crp- q and/or hs- crp and wbc c...