نتایج جستجو برای: b22
تعداد نتایج: 150 فیلتر نتایج به سال:
We describe the modification of the side chain of the arginine-B22 residue of insulin by the N8N9-(1, 2-dihydroxycyclohex-1,2-ylene) group and by the adipoyl group. These are the first insulin derivatives described that contain a modified arginine residue in an otherwise unaltered molecule. When tested for their ability to lower blood sugar concentration, both modified insulins showed a specifi...
The reversible reaction of cyclohexane-1,2-dione with the guanidino function of Arg-B22 in bovine insulin gave the dihydroxycyclohexylene [DHCH]-Arg-B22-insulin complex (I) which, after selective tryptic cleavage at the Lys-B29 residue and regeneration of the guanidino group, afforded bovine des-AlaB30-insulin (III) in an overal 85.80/o yield. The truncated insulin III was converted into the re...
A series of chalcones a1-20 bearing a 4-OMe groups on the A-ring were initially synthesized and their anticancer activities towards HepG2 cells evaluated. Subsequently, a series of chalcones b1-42 bearing methoxy groups at the 2' and 6'-positions of the B-ring were synthesized and their anticancer activities towards five human cancer cell lines (HepG2, HeLa, MCF-7, A549 and SW1990) and two non-...
Monoclonal antibody TG1 recognizes specifically antigens HLA-B27, B7, B22 and B17 on cell surface in cytotoxicity and cytofluorometry tests. When cell detergent extracts were subjected to SDS PAGE under mild conditions (no heating and no reduction of the sample) followed by Western blotting, TG1 detected exclusively a complex of B27 heavy chains with beta(2)-microglobulin (as a 50 kDa band) whe...
in this study, the neutral monosaccharide composition of the extracellular polysaccharide (eps), extracted from thermal bacillus, was determined by liquid chromatography-mass spectrometry and high performance liquid chromatography. our analysis indicated that the eps consisted of rhamnose, mannose, galactose, glucose, fructose, arabinose and xylose. in addition to the neutral sugars in the eps,...
Infections with monkeypox, cowpox and weaponized variola virus remain a threat to the increasingly unvaccinated human population, but little is known about their mechanisms of virulence and immune evasion. We now demonstrate that B22 proteins, encoded by the largest genes of these viruses, render human T cells unresponsive to stimulation of the T cell receptor by MHC-dependent antigen presentat...
I argue that it is microeconomics that needs foundations, not macroeconomics. Preferences need to be built on biology, and, in particular, on neuroscience. In contrast, macroeconomics could benefit from rationalizations of aggregate economic phenomena by non-equilibrium statistical physics. Special issue Reconstructing Macroeconomics JEL: B22, B41, C82, D87
1 Research Group of Plant and Vegetation Ecology, Department of Biology, Universiteit Antwerpen (Campus Drie Eiken), Universiteitsplein 1, 2610 Wilrijk, Belgium 2 Division Soil and Water Management, Faculty of Bioscience Engineering, Katholieke Universiteit Leuven, Kasteelpark Arenberg 20, 3001 Leuven/Heverlee, Belgium 3 Laboratory of Plant and Microbial Ecology, Institute of Plant Biology B22,...
B22 Osteosarcoma Subtypes in Osteosarcoma Patients with Multiple Primary Malignancies. Can Rare Subtypes be Indicative for Cancer Syndromes Related with Osteosarcoma? E.I. Hauben1, J.J. Arends2, J.P. Vandenbroucke2, C. van Asperen2, E. van Marck3, P.C.W. Hogendoorn2 1Stichting PAMM, Eindhoven, The Netherlands, 2Leiden University Medical Center, Leiden, The Netherlands, 3Universitair Ziekenhuis,...
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