background: mycobacterium tuberculosis is a major cause of mortality and morbidity worldwide. infection with this bacterium is known to induce the development of autoantibodies of which a few are also known to be diagnostic markers for some other diseases. antineutrophil cytoplasmic antibodies (anca's) are among those autoantibodies used in clinical setting for diagnosing systemic vasculit...

anti-neutrophil cytoplasmic autoantibodies have been detected in patients with some autoimmune and vascular diseases such as wegner's granulomatosis, polyarthritis nodosa and systemic lupus erythematosus. indirect immunofluorescence technique has been employed to detect these autoantibodies. by this method, two general patterns of antineutrophil cytoplasmic antibodies were seen: a cytoplasmic (...

Sir, A 45-year-old man was admitted with history of painful, sequential multiple peripheral nerve involvement for four months. On questioning he revealed history of allergic rhinitis with recurrent nasal polyps, bronchial asthma for two years, weight loss, joint pains with swelling and Raynaud’s phenomenon of four months duration. Examination revealed skin rash and features of mononeuritis mult...

Background: Mycobacterium tuberculosis is a major cause of mortality and morbidity worldwide. Infection with this bacterium is known to induce the development of autoantibodies of which a few are also known to be diagnostic markers for some other diseases. Antineutrophil Cytoplasmic Antibodies (ANCA's) are among those autoantibodies used in clinical setting for diagnosing systemic vasculitic sy...

BACKGROUND Propylthiouracil is the most common drug used to treat hyperthyroidism. However, this drug could cause a severe disease, antineutrophilic cytoplasmic antibody-associated vasculitis (AAV), which was usually misdiagnosed. METHODS We reported a 60-year-old woman of propylthiouracil-induced AAV manifested as blood coagulation disorders. The patient was admitted because of hyperthyroidi...