The traditional medicine, Cassia alata, also known as Ketepeng Cina in Indonesia and Gelenggang Malaysia, has been used to cure a variety of illnesses particularly skin conditions. Additionally, it suggested that C. alata may have antifungal, anticancer, anti-inflammatory, antioxidant properties. Alatinon, alanonal, flavones, flavonols, flavonoid glycosides, well -sitosterol-D-glucoside, are am...

An antifungal metabolite, oosporein, was isolated from the culture of Verticillium psalliotae that produced the antagonistic effects on Phytophthora infestans. Oosporein exhibited a significant growth-inhibitory effect on P. infestans in comparison with other phytopathogenic fungi.

Phytochemical screening and antifungal activity test of jengkol leaf (Archidendron jiringa) extract have been carried out. The purpose this research is determine secondary metabolite content activities extract. Extraction was conducted with sequential extraction technique various solvent such as hexane, ethyl acetate methanol respectively. FTIR characterization show the presence O-H, C-H C-O C=...

To date six antifungal antibiotics of the strobilurin-type are known (Scheme 1): Strobilurin A (1)1>2) which is identical with mucidin3), strobilurin B (2)ia\ strobilurin C (3)4), methoxymucidin (4)5), hydroxystrobilurin D6) and strobilurin E7). They contain an unsaturated side chain with a terminal (£)-/?-methoxyaerylate moiety and differ usually in their aromatic substitution. In the precedin...

Brassilexin and sinalexin are among the most potent antifungal phytoalexins produced by crucifer plants. Nonetheless, the crucifer pathogen Leptosphaeria maculans(Desm.) Ces. et de Not. (asexual stage Phoma lingam(Tode ex Fr.) Desm.) is able to detoxify these phytoalexins. To understand and control these reactions, the elusive brassilexin and sinalexin detoxification pathways in L. maculans wer...

Marine fungi producing antifungal compounds were screened against Pyricularia oryzae (P. oryzae), and a metabolite of marine fungus M-3 isolated from laver (Porphyra yezoensis) showed potent activity. Novel diketopiperazine (1) was isolated from the culture extracts, and its structure was elucidated by spectroscopic methods. The MIC of 1 against P. oryzae was 0.36 microM.

Ten metabolites produced by 4 mutants derived from Actinomadura verrucosospora subsp. neohibisca E-40, a high pradimicins producer, were isolated and their structures were determined. Strain JN-219 produced 3 novel analogs of the pradimicin A aglycone, i.e. 11-O-demethyl-7-methoxypradinone II and 11-O-demethylpradinones I and II together with a known aglycone analog, pradinone I, while the meta...

Kitasatospora cheerisanensis KCTC 2395, which produces antifungal metabolites with bafilomycin derivatives, including bafilomycin C1-amide, was isolated from a soil sample at Mt. Jiri, South Korea. Here, we report its draft genome sequence, which contains 8.04 Mb with 73.6% G+C content and 7,810 protein-coding genes.