The current study is a systematic review of the literature concerning the possible relationship of antiepileptics and suicide-related clinical features and behaviours. A MEDLINE search returned 863 papers but only five were chosen as relevant. A critical analysis of the Food and Drug Administration report is also included. Overall, the current review suggests there are no convincing data concer...

Epilepsy has become second most common neurological disorder affecting 70 million people worldwide. Several shortcomings appeared with the use of conventional antiepileptic drugs (AEDs) like, inadequate seizure control, side effects, cost, potentiation of epilepsy-induced co-morbidities, etc., which limit their use as comprehensive therapy. Phytoflavonoids in this regard have been observed to b...

Neurocysticercosis (NCC) is a parasitic infection with the larvae of Taenia solium from contaminated pork. It is a leading cause of seizures in the developing world. Symptoms may be secondary to live or degenerating cysts, or previous infection causing calcification or gliosis. Diagnosis is based on clinical presentation, radiological confirmation of intracranial lesions and immunological testi...

The changes of electroencephalogram induced by maximal electroshock were studied in comparison with behavioral seizures in mice. After electroshock, mice showed tonic flexor (TF) seizure, tonic extensor (TE) seizure, and clonic (CL) seizure, in this order of occurrence. At the same time, high frequency spike or spike and wave complex in the cortex was observed, and thereafter, the frequency of ...

background and objective: n-methyl-d-aspartate (nmda) antagonists such as piperidines are the most important antiepileptic drugs. considering the fact that piperidine derivatives such as phencyclidine (pcp) and its new derivative, 1-[1-(3-methoxyphenyl) (tetralyl)] piperidine (pcp1), have different potencies, the antiepileptic effects of mentioned drugs were investigated in the present study. ...