We report the use of microfluidic rapid mixing using hydrodynamic flow focusing to control the self-assembly of polymeric nanoparticles (NPs) that can be used for drug delivery. PLGA-PEG polymeric NPs and PLGA-lipid hybrid NPs were synthesized through nanoprecipitation—a process that involves dilution of a block copolymer from a solvent to an anti-solvent resulting in the precipitation of NPs. ...

Cinnamon is the bark the cinnamomi cassia that exhibits many medical properties such as anti-cancer effect and anti-diabetic effect. Moreover, because of its antioxidant activity; it can be used in food industries. Many studies have already reported biological and chemical properties of the cinnamon extracted essential oil such as their antimicrobial, antifungal, antimosquito, free radical scav...

Our aim in the present study was to evaluate the anti-lipase and anti-obesity activities of Terminalia Paniculata in high caloric diet (HCD) induced obese rats. Different solvent extracts (Hexane, ethyl acetate, ethanolic and aqueous) were prepared from the bark of T. paniculata and tested for their lipase inhibiting and anti-obesity activities. Among the extracts tested, ethanolic extract show...

the ionic liquid, n,n,n,n-tetramethylguanidiniumtriflate (tmgtf) was found to be an efficient catalyst solvent for henry reaction between nitromethane and isatin derivatives to provide 3-hydroxy-3-(nitromethyl)indolin-2-one under mild conditions. the ionic liquid amenable to successive recycling without appreciable decrease in activity. synthesized compounds have been screened for their anti-di...

Anti-solvent crystallization can be used as an alternative to cooling or evaporation for the separation and purification of solid product in the pharmaceutical industry. Addition of antisolvent reduces the solubility of a solute in solution thereby facilitating the generation of supersaturation, the driving force for nucleation and growth. Some of the problems associated with anti-solvent cryst...

Phycocyanin (PC) is a bioactive compound that can function as an antioxidant, anti-inflammatory, immunomodulatory, and anti-cancer agent. It act potential material in preventing COVID-19 curing those suffering from it. Spirulina platensis (SP) one of the microalgae rich proteins PC. This study aimed to determine optimum PC extraction SP, using distilled water solvent through freezing-thawing pr...

While ionic liquids (ILs) have been considered as effective and “green” solvents for biopolymer processing, regeneration of IL-dissolved biopolymers could largely impact structure properties. This study indicates that the reconstitution chitosan during from 1-ethyl-3-methylimidazolium acetate ([Emim][OAc]) depends on anti-solvent (water, methanol or ethanol) largely. Irrespective anti-solvent, ...