Toxoplasmosis is an opportunistic infection caused by Toxoplasma gondii (TG), which affects one third of the global human population and commonly involves central nervous system (CNS)/brain despite so-called CNS immune privilege. Symptomatic clinical disease TG much more associated with immunodeficiency; clinicopathological manifestations toxoplasmosis are linked to individual responses includi...

Introduction: Toxoplasma gondii (T. gondii) is distributed worldwide and infects most species. The serious incidence and severe or fatal injury caused by T. gondii infection clearly indicates the necessity for the event of a vaccine. The current study goals were to evaluate serological applications of Toxoplasma gondiirhoptry protein 1 (ROP1) ...

Abstract Introduction: Toxoplasmosis is a disease of global distribution caused by the parasite Toxoplasma gondii, which develops differently depending on immunologic status patient. In immunocompetent patients, it usually asymptomatic and complications such as pneumonitis, encephalitis, or multiple organ dysfunction are rare. The following case an patient with acute disseminated toxoplasmosis....

Toxoplasmosis has been associated with economic and public health concerns due to abortion in humans animals. Detection for the presence of anti-Toxoplasma gondii antibodies sera 174 healthy sheep (IgG) 89 aborted women (IgG, IgM, IgG avidity) using enzyme-linked immunosorbent assay T. 59 milk samples identified by PCR. The primary risk factors seropositive were also analyzed. Relatively higher...

Congenital toxoplasmosis is an established cause of abortion, neonatal disease and ocular defects presenting in later life. Preventative options include health education, immunization and screening of pregnant women and infants with appropriate management of cases found to be at risk. Screening requires a knowledge of the disease, the test, the treatment and the administration of the proposed p...

Four patients with toxoplasmosis are reported with unusual presenting ocular lesions. One patient had an active lesion that appeared to involve the optic nerve as well as focal toxoplasmosis chorioretinitis at the macula. A second patient had a pale optic nerve in association with the classical chorioretinal scars of toxoplasmosis. The third patient had toxoplasmosis chorioretinitis of the macu...

introduction: toxoplasmosis is a parasitic infection cause by toxoplasma gondii. this parasite is associated with congenital infection and can cause abortion, encephalitis or systemic infection in immune- compromised patients. case presentation in this study, two cases of central nervous system toxoplasmosis in leukemia patients are reported. the first case was a 15-year-old girl with acute lym...

The main serological marker for the diagnosis of recent toxoplasmosis is the specific IgM antibody, along with IgG antibodies of low avidity. However, in some patients these antibodies may persist long after the acute/recent phase, contributing to misdiagnosis in suspected cases of toxoplasmosis. In the present study, the diagnostic efficiency of ELISA was evaluated, with the use of peptides de...

Manuls or Pallas' cats (Felis manul, syn. Otocolobus manul) are endangered wild cats from Central Asia kept and bred in many zoos. Despite good breeding success young cats frequently die from acute toxoplasmosis. From 1998 to 2002, a breeding pair in the Schönbrunn Zoo in Vienna, Austria, gave birth to 24 kittens; 58 % of kittens died between the 2nd and the 14th week of life, mostly due to acu...

Toxoplasma gondii SAG1, GRA1, and GRA7 recombinant antigens may be regarded as tools for the detection of T. gondii immunoglobulin G antibodies in persons with chronic and acute toxoplasmosis. GRA7 is more correlated with acute toxoplasmosis. A combination of these antigens will increase the sensitivity of enzyme-linked immunosorbent assays.