Intrinsic resistance to existing clinical platinum drugs is a major cause of treatment failure; moreover, these agents have the drawbacks of cross-resistance and intravenous administration. The mechanism of intrinsic cisplatin resistance and the mechanism of circumvention of intrinsic resistance by a member (JM221) of the ammine/amine platinum (IV) dicarboxylate class of platinum complex was st...

A description of the new N a t ional Bureau of Standards " low" en ergy free-air chamber is given. The standard chamber is designed to mea sure t l1e expos ure dose II: roe ntgens for X-ray beams generated at pote ntials fr ol11. 20 to 100 kIi ovolts-co nstant-poten tJaI (kvcp) '':Ith filtration s ranging from 2 millimet e rs of bery lli um to 2 mIi lune ters of b ery l hum plus 41m 11Ime ters ...

The purpose of the study is comapring musculoskeletal system complaints, fatigue, and sleep quality in front-line second-line healthcare workers treating for COVID patients. 152 between ages 18 65 who worked outpatient clinics, services, Covid-19 units, or administrative management were included this study. Health involved diagnosis, treatment, isolation patients diagnosed with determined as (2...

Although deep learning has achieved remarkable successes over the past years, few reports have been published about applying neural networks to Wireless Sensor Networks (WSNs) for image targets recognition where data, energy, computation resources are limited. In this work, a Cost-Effective Domain Generalization (CEDG) algorithm proposed train an efficient network with minimum labor requirement...

In direct steam generation (DSG) concentrated solar power (CSP) plants, a common thermal energy storage (TES) option relies on accumulation. This conventional is constrained by temperature and pressure limits, delivers saturated or slightly superheated at reduced during discharge, which undesirable for part-load turbine operation. However, accumulation can be integrated with sensible-heat in co...

The in vitro cytotoxicities of a number of gold(I), silver(I) and copper(I) complexes containing chiral tertiary phosphine ligands have been examined against the mouse tumour cell lines P815 mastocytoma, B16 melanoma [gold(I) and silver(I) compounds] and P388 leukaemia [gold(I) complexes only] with many of the complexes having IC(50) values comparable to that of the reference compounds cis-diam...