نتایج جستجو برای: 353
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Cytochrome P450 enzymes from the CYP2C subfamily play a prominent role in the metabolic clearance of many drugs. CYP2C enzymes have also been implicated in the metabolism of arachidonic acid to vasoactive epoxyeicosatrienoic acids. CYP2C8, CYP2C9, and CYP2C19 are expressed in the adult liver at significant levels; however, the expression of CYP2C enzymes in extrahepatic tissues such as the brai...
Background: Total folate intake includes naturally occurring food folate and folic acid from fortified foods and dietary supplements. Recent reports have focused on total folate intakes of persons aged 14 y. Information on total folate intakes of young children, however, is limited. Objective: The objective was to compute total folate and total folic acid intakes of US children aged 1–13 y by u...
Motor neuron degeneration resulting from the aggregation of the androgen receptor with an expanded polyglutamine tract (AR-polyQ) has been linked to the development of spinal and bulbar muscular atrophy (SBMA or Kennedy disease). Here we report that adding 5-hydroxy-1,7-bis(3,4-dimethoxyphenyl)-1,4,6-heptatrien-3-one (ASC-J9) disrupts the interaction between AR and its coregulators, and also in...
Received: July 2005. Accepted: January 2006. Aim. To value the technical complications associated with Seidel’s intramedullary nailing using in the management of humeral diaphyseal fractures. Materials and methods. Retrospective study of 43 cases, controlled between the year 1999 and 2003, analyzing epidemiological, clinical-radilogical parameters, as well as the most frequent complications and...
We have recently found that analog V (BXL-353, a calcitriol analog) inhibits growth factor (GF)-stimulated human benign prostate hyperplasia (BPH) cell proliferation by disrupting signal transduction, reducing Bcl-2 expression, and inducing apoptosis. We now report that BXL-353 blocks in vitro and in vivo testosterone (T) activity. BPH cells responded to T and dihydrotestosterone (DHT) with dos...
Abstract Introduction An exoscope is a next generation HD telescope video monitoring system used to perform microsurgeries that now formidable rival the existing operating microscope in neurosurgery. While revolutionised neurosurgery with its advent 1957, allows surgeons operate utilising high-definition images enhancing field of vision and focus. The opens new avenues regards ergonomics, teach...
A novel actinobacterial strain, MBRL 353(T), was isolated from a sample collected from a limestone quarry at Hundung, Manipur, India. Comparison of 16S rRNA gene sequences of strain MBRL 353(T) and other members of the genus Rhodococcus showed sequence similarities ranging from 95.5 to 98.2 %, with strain MBRL 353(T) showing closest sequence similarity to Rhodococcus triatomae IMMIB RIV-085(T) ...
Cytology in General Practice H. C. McLaren, F.R.C.O.G..... 350 Chronic Prostatitis Surgeon Commander N. J. Blacklock, F.R.C.S., and D. S. Reeves, M.R.C.PATH. 351 Trapped Nerves W. V. Applegate, M.D............................351 Distress of Dying R. C. Lamerton, M.R.C.S......................351 Alpha-fetoprotein and Gastric Carcinoma C. M. Castleden, M.R.C.P., and J. D. Davies, M.D . .............
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