Dysexpression of microRNAs has been found in many tumors, including lung cancer. The hedgehog (Hh) signaling pathway plays an important role during normal development, and the abnormal regulation of its members has also been related to many tumors. However, little is known about the relationship between microRNA and the Hh pathway. In this paper, we report microRNA-212 (miR-212) playing a role ...

MicroRNAs have been found to be critical regulator of cancer cell biology. MicroRNA-212 (miR-212) was identified to be a critical cancer-associated microRNA playing either oncogenic functions or tumor suppressive roles in different types of human cancers. In this study, we found that the level of miR-212 in renal cell carcinoma (RCC) tissues was significantly lower than that in adjacent non-tum...

The authors describe the effects of practice conditions in motor learning (e.g., contextual interference, knowledge of results) within the constraints of 2 experimental variables: skill level and task difficulty. They use a research framework to conceptualize the interaction of those variables on the basis of concepts from information theory and information processing. The fundamental idea is t...

Sexual Bias and Household Consumption: A Semiparametric Analysis of Engel Curves in Rural China We analyze Engel curves for nuclear households in rural China. The sample includes more than 5000 nuclear families covering nineteen out of thirty Chinese provinces. We consider expenditures on food, also subdivided into several food subcategories such as cereals, or meat and fish, and other consumpt...

We formulate and study a mechanical instability criterion for sudden hadronization of dense matter fireballs formed in 158A GeV Pb-Pb collisions. Considering properties of quark-gluon matter and hadron gas we obtain the phase boundary between these two phases and demonstrate that the required deep quark-gluon-plasma supercooling prior to sudden hadronization has occurred.

BACKGROUND Multiple MicroRNAs (miRNAs) have been identified in the development and progression of osteosarcoma. However, the expression and roles of miR-212 in osteosarcoma remain largely undefined. METHODS Real-time PCR assays were used to detect the expression of miR-212 in human osteosarcoma tissues. MiR-212 mimics were introduced into MG63 and U2OS cells. Bioinformatic prediction was used...

The problem of large-scale correlations of particles produced in high-energy collisions is discussed. Among them are, e.g., those correlations which lead to ring-like and elliptic flow shapes of individual high-multiplicity events in the polar+azimuthal angles plane. The wavelet method of analysis which allows to disentangle various patterns is proposed and applied to central Pb-Pb collisions a...

MicroRNA-212 (miR-212) has been reported to play oncogenic or tumor suppressive role in different human malignancies. Here, we demonstrated that the mean level of miR-212 in hepatocellular carcinoma (HCC) tissues was significantly lower than that in matched tumor-adjacent tissues. Similarly, the expression of miR-212 was obviously reduced in HCC cell lines as compared with a nontransformed hepa...