Drug discovery, development and registration is an expensive and time-consuming process associated with a high failure rate [Pessetto et al. (Mol Cancer Ther 12:1299-1309, 2013), Woodcock and Woosley (Annu Rev Med 59:1-12, 2008)]. Drug 'repurposing' is the identification of new therapeutic purposes for already approved drugs and is more affordable and achievable than novel drug discovery [Pesse...

Address for correspondence: Tchavdar N. Shalganov, MD, Cardiology Department, National Heart Hospital, 65, Koniovitsa Street, 1309 Sofia, Bulgaria, tel: +359 2 92 11 356; fax: +359 2 822 31 88; e-mail: [email protected] Substrate-based catheter ablation in previously undiagnosed arrhythmogenic right ventricular dysplasia by means of an electroanatomic mapping system using cutaneous p...