Abstract Fibronectin 1-derived circular RNA hsa_circ_0058092 is a novel potential oncogene in gastric cancer (GC). Yet, previous studies have not determined the role of GC progression and underlying mechanism. Herein, we investigated its competing endogenous (ceRNA) pathway development GC. The results showed that was substantially upregulated patients’ tissues cells, allied with SIX1 downregula...

This study investigated interactive effects of CYP2B6 genotypes and liver metastasis on the prognosis of metastatic breast cancer patients who received combined chemotherapy of docetaxel and thiotepa. Totally 153 patients were retrospectively genotyped rs8192719 (c.1294 + 53C > T) and rs2279343 (c.785A > G). Kaplan-Meier method and Cox Proportional Hazard Regression model were used to estimate ...

An evaluation of a recent study by Asfar P, Meziani F, Hamel J-F, . et al High . N Engl J versus low blood-pressure target in patients with septic shock Med 2014;370:1583-1593. This article is included in the channel. Critical care Michael Pinsky ( ) Corresponding author: [email protected] Kato R and Pinsky M. How to cite this article: Where is the vascular waterfall in septic shock? [version 1...

INTRODUCTION ............................................................................................. 1289 I. THE NATURE AND COMPONENTS OF FIDUCIARY RELATIONSHIPS AND THE RISKS THE RELATIONSHIPS POSE TO BOTH PARTIES .......... 1293 A. Components of Fiduciary Relationships .................................... 1293 B. While Fiduciaries’ Services Provide Benefits to Entrustors, the Services I...

The effectiveness of a probiotic formulation applied in human vagina depends on the possibility of adaptation of the beneficial microorganisms in this environment. The understanding of the interactions of potentially probiotic microorganisms with the vaginal fluid, which shows some specific physical and chemical properties, can help to the design of improved vaginal probiotic formulations. The ...