Three major autophosphorylation sites are located near the C-terminus of the epidermal growth factor receptor, but a fourth site is repeatedly detected. We report here the purification and sequencing of a tryptic peptide containing this site, Tyr-1086. Furthermore, we demonstrate that additional phosphopeptides are observed following both partial digestion and overdigestion. Finally, we show th...

Introduction........................................................................................................ 1062 Part I. What the Restatement (Third) Has Already Addressed, or Will Address.................................................................................... 1063 Part II. A Selective Review of Doctrinal Developments ................................. 1065 A. Battery .........

Mediated Mechanism − Tyrosine Phosphatase 1B NO Attenuates Insulin Signaling and Motility in Aortic Smooth Muscle Cells via Protein Print ISSN: 1079-5642. Online ISSN: 1524-4636 Copyright © 2002 American Heart Association, Inc. All rights reserved. Greenville Avenue, Dallas, TX 75231 is published by the American Heart Association, 7272 Arteriosclerosis, Thrombosis, and Vascular Biology doi: 10....

We studied the influence of the aromatic sidewalls on the ability of acyclic CB[n]-type molecular containers (1a-1e) to act as solubilizing agents for 19 insoluble drugs including the developmental anticancer agent PBS-1086. All five containers exhibit good water solubility and weak self-association (Ks ≤ 624 M(-1)). We constructed phase solubility diagrams to extract Krel and Ka values for the...

The existence of regulatory molecules derived from T cells, which play an important role in the control of immune reactions, has been documented in a number of experimental systems (1-4). Such T-cell-derived regulatory molecules appear to share many biochemical properties which would argue for their structural and functional similarity (3, 4). These common properties support the notion that sim...

0096-3003/$ see front matter 2010 Elsevier Inc. All rights reserved. doi:10.1016/j.amc.2010.01.129 * Corresponding author. E-mail address: [email protected] (Z.C. Zheng). Applied Mathematics and Computation 216 (2010) 1072–1086