Infections caused by potentially drug-resistant pathogens steadily increase in intensive care units (ICUs) and are a major cause of overall prevalence in hospitals. Resistance is likely because ICU patients often have complex illnesses and use many antibiotics.(1,2) Indeed, more than 70% of critically ill patients will be given an antimicrobial drug during their ICU stay.(1) In addition, infect...

Perhaps the best known example of a random set is the Boolean model. It is the union of ‘grains’ such as discs, squares or triangles which are placed at the points of a Poisson point process. The Poisson points are are called the ‘germs’. We are interested in estimating the intensity, say lambda, of the Poisson process from a sample of a Boolean model of discs (the bombing model). A natural est...

ion of blood tolerated. Albuminous urine the exception. Liver not affected. Spleen invariably affected. Suppression of urine the exception. Haemorrhages from stomach in bad cases the exception. Antagonistic power of quinine J)eyond the reach of question. Death seldom occurs before the seventh day. Remittent merges into intermittent. One attack affords no immunity from future ones. No immunity o...

Mandibular second molar tooth germs from two-day old mice were cultured in vitro, on millipore membranes, for periods of up to 20 days in liquid medium with or without added ascorbic acid. Tooth germs grown in ascorbate medium were characterized by relatively normal growth, differentiation, morphology and histology. Cuspation patterns were maintained. The epithelial root sheath continued to gro...

Effective germ elimination during endodontic treatment is absolutely necessary1,2 because treatment failure can often be attributed to the inadequate reduction of germs. The bacterial flora in endodontic infections is related to the flora in the oral cavity and has a bacterial population of between 102 and 107 different germs per infected root canal.3 Since mechanical preparation of the root ca...

The area of the oral vestibule is often a place where pathologies appear (e.g., peripheral odontomas). The origin of these pathologies is not fully understood. In the present study, we traced a cell population expressing Sonic hedgehog (Shh) from the beginning of tooth development using Cre-LoxP system in the lower jaw of wild-type (WT) mice. We focused on Shh expression in the area of the earl...

In this work we study the Positive Extension (PE) property and Hilbert’s 17th Problem for real analytic germs and sets. A real analytic germ Xo of Ro has the PE property if every positive semidefinite analytic function germ on Xo has a positive semidefinite analytic extension to Ro ; analogously one states the PE property for a global real analytic set X in an open set Ω of R. These PE properti...

Perhaps the best known example of a random set is the Boolean model. It is the union of `grains' such as discs, squares or triangles which are placed at the points of a Poisson point process. The Poisson points are called the `germs'. We are interested in estimating the intensity, say lambda, of the Poisson process from a sample of a Boolean model of discs (the bombing model). A natural estimat...

We discuss canonical bases in theories with a rudimentary notion of independence. We characterize when canonical bases exist for an ominimal theory, and we also study germs of definable multi-functions at definable types in the general case.