Antihistamines are commonly used to treat allergic disease, such as allergic rhinitis, urticaria, and angioedema. Although several previous reports describe hypersensitivity to antihistamines such as cetirizine and hydroxyzine, documented cases of chlorpheniramine hypersensitivity are extremely rare. Here, we report the case of a 45-year-old Korean woman who presented with urticaria after inges...

BACKGROUND Many physicians believe that the most effective way to treat chronic urticaria is to take a nonsedating second-generation H1 -antihistamine in the morning and a sedating first-generation H1 -antihistamine, usually hydroxyzine, at night to enhance sleep. But is this belief well founded? OBJECTIVES To test this belief by comparing the effectiveness and prevalence of unwanted sedative...

Urticaria is a kind of skin rash that sometimes caused by allergic reactions. Acute viral infection, stress, pressure, exercise and sunlight are some other causes of urticaria. However, chronic urticaria and angioedema could be either idiopathic or caused by autoimmune reaction. They last more than six weeks and could even persist for a very long time. It is thought that the level of C-reactive...

BACKGROUND Urticaria and anaphylaxis are frequently encountered in veterinary practice, but little is known about the causes and relative frequencies of these reactions. HYPOTHESIS/OBJECTIVES This study was designed to improve current knowledge on the triggers, risk factors and clinico-pathological features of urticaria. ANIMALS Twenty four dogs with signs of urticaria with or without anaph...

Hydatid cyst is still endemic in various regions of the world. It is the most frequent cause of liver cysts worldwide. Urticaria is sometimes the first manifestation of the disease. However anaphylactic reaction and urticaria have been very rarely reported in the literature. Traditionally, surgery has been the only accepted mode of treatment; however, percutaneous treatment has recently been pr...

Although there are several studies showing the association between cancer and urticaria, the mechanisms by which these events occur are not yet known. In this report, a case of acute urticaria with a diagnosis of thyroid papillary carcinoma is presented. Disappearance of treatment-resistant urticarial lesions after thyroidectomy suggests that this association was not a coincidence. The fact tha...

Cold contact urticaria is the second most common subtype of physical urticaria. Cold stimulation standardized tests are mandatory to confirm the diagnosis. The aim of this study is to define the utility of determining thresholds (critical time and temperature) in assessment of the clinical course of typical acquired cold contact urticaria. Nineteen adult patients (10 women and 9 men; mean age 4...

PURPOSES This study's aim was to determine the predictive factors of the duration of first-attack acute urticaria in children. BASIC PROCEDURES The sample included 1075 children admitted to the emergency department with first-attack acute urticaria. Variables comprising the clinical features and past histories of children with duration of disease of 3 days or less, 4 to 7 days, 8 to 14 days, ...

We report a case of a 45 year old woman which fulfilled the criteria of chronic urticaria (remitting and relapsing bouts of erythematous and pruriginuos lesions without angioedema, lasted four months). Cutaneous manifestations were not related to a specific inducing factor, had no benefit from antihystamine and steroid drugs and were associated sometimes with mild gastroentric disorders. Patien...

OBJECTIVE To determine the frequency of autoimmune thyroid disease in diagnosed cases of chronic urticaria (CU) and the association between hypothyroidism and chronic urticaria if any. STUDY DESIGN Non-interventional, descriptive study. PLACE AND DURATION OF STUDY Department of Physiology, Dow University of Health Sciences, Karachi, from December 2004 to January 2006. METHODOLOGY The pati...