Improved glucose tolerance to sequential glucose loading (Staub-Traugott effect) is an important determinant of day-to-day glycemic exposure. Its mechanisms have not been clearly established. We recruited 17 healthy volunteers to receive two sequential oral glucose tolerance tests (OGTTs), at time 0 min and 180 min (Study I). The protocol was repeated on a separate day (Study II) except that pl...

The cytocidal action of Naja naja kaouthia venom on rabbit red blood cells and S-180 tumor cells treated with local anesthetics (tetracaine, lidocaine and procaine) were studied. The S-180 cells were more sensitive to the venom than the red blood cells which required albumin for efficient hemolysis in the 10 minute assay. All three local anesthetics at lower concentrations protected both cell t...

AIMS Saxagliptin reduced glycated hemoglobin (HbA1c), fasting plasma glucose (FPG), and postprandial glucose (PPG) in Asian patients with type 2 diabetes mellitus (T2DM). To understand the physiology of this effect, indices of α- and β-cell function were measured in a subpopulation of Chinese patients following a noodle mixed-meal tolerance test. METHODS Data from Chinese patients were pooled...

Antibody-mediated C-dependent lysis of cell lines infected with herpes simplex type 1 virus, influenza A degrees virus, measles virus, and mumps virus occurred by the alternative C pathway with the participation of IgG antibodies. Lysis occurred only with immune human sera, Mg++ EGTA immune sera, and immune sera depleted of C4 or treated with Fab anti-C4. Lysis did not occur with nonimmune sera...

BACKGROUND To determine the acute effects of ingesting a thermogenic drink (Celsius, Delray Beach, FL) (TD) on changes in metabolism and lipolysis. METHODS Healthy college-aged male (23.2 +/- 4.0 y, 177.2 +/- 6.1 cm, 81.7 +/- 11.3 kg, 22.8 +/- 7.3 % fat; n = 30) and female (23.4 +/- 3.1 y, 165.6 +/- 8.7 cm, 62.1 +/- 9.9 kg, 28.3 +/- 7.4 % fat; n = 30) participants were matched according to he...

Muscle mass inversely relates to 2 hours glucose levels after oral glucose load in non-diabetic subjects. A study in glucose intolerance subjects has never been performed. We conducted this study to determine the relationship between muscle mass and glucose level after oral glucose load in glucose intolerance subjects. Sixty Thai subjects, 44 drug-naïve, newly diagnosed type 2 diabetes mellitus...

The aim of this work is to investigate the effect of thermal treatment on the grinding behavior of manganese ore in the various size fractions of -1.7+1.18, -1.18+0.6, -0.6+0.3 and -0.3+ 0.15 mm. Breakage Function Determination Software (BFDS) is used to calculate the selection function of the experiment. The results of SEM analysis show the micro-cracks in the thermally treated manganese sampl...

All dsDNA phages encode two proteins involved in host lysis, an endolysin and a holin that target the peptidoglycan and cytoplasmic membrane, respectively. Bacteriophages that infect Gram-negative bacteria encode additional proteins, the spanins, involved in disruption of the outer membrane. Recently, a gene located in the lytic cassette was identified in the genomes of mycobacteriophages, whic...

Previous reports have established that line 1, a spontaneous BALB/c lung carcinoma, expresses a M, 180,000 tumor-associ ated surface antigen (TSP-180). In this study, using a monoclonal antibody and flow cytometry to quantify cell surface TSP-180 expression, we found that essentially all cells in a tissue cultureadapted line 1 population express TSP-180, but that the amount of TSP-180 expressed...