نتایج جستجو برای: tdt
تعداد نتایج: 2244 فیلتر نتایج به سال:
Big Data is revolutionizing nearly every aspect of our lives ranging from enterprises to consumers, from science to government. On the other hand, cloud computing recently has emerged as the platform that can provide an effective and economical infrastructure for collection and analysis of big data produced by applications such as topic detection and tracking (TDT). The fundamental challenge is...
Topic Detection and Tracking (TDT) on Twitter emulates human identifying developments in events from a stream of tweets, but while event participants are important for humans to understand what happens during events, machines have no knowledge them. Our evaluation football matches basketball games shows that tweets is difficult problem exacerbated by Twitter’s noise bias. As result, traditional...
Homologous recombination (HR) in somatic cells serves as a protective mechanism for the genome against unanticipated double-strand breaks DNA. While HR is generally scarcely detectable metazoans, it observed skin under certain pathological conditions, such revertant patches of “ichthyosis with confetti”, lesional “disseminated porokeratosis”, and cancer cells. These observations suggest that no...
Background. The development of periodontitis is strongly linked with both periodontopathogenic microflora and antioxidant-proxidant system disorders, which determines the need for combined use antimicrobial antioxidant agents. Objectives. A comparative evaluation antioxidant-prooxidant red blood cells in rats experimental against background traditional drug therapy its combination Soderm®-Forte...
Young adult Lewis rats were maintained on diets containing 0.015 or 0.027% cyclosporin A (CSA) for periods of up to 6 wk. All animals showed complete depletion of medullary thymocytes (CD4+8- and CD4-8+, T cell receptor [TCR] alpha/beta hi, Thy-1med/low, terminal deoxynucleotidyl transferase negative [TdT-]) and a 50% reduction in the number of TdT- cortical thymocytes (CD4+8+, TCR alpha/beta l...
Many neurons in Alzheimer's disease (AD) exhibit terminal deoxynucleotidyl transferase (TdT) labeling for DNA strand breaks with a distribution suggestive of apoptosis. We have shown previously that immunoreactivity for c-Jun is elevated in AD and found in association with neuronal pathology. In addition, cultured neurons undergoing beta-amyloid-mediated apoptosis exhibit a selective and prolon...
Type 1 diabetes is a common polygenic disease. Fine mapping of polygenes by affected sibpair linkage analysis is not practical and allelic association or linkage disequilibrium mapping will have to be employed to attempt to detect founder chromosomes. Given prior evidence of linkage of the Jk-D18S64 region of chromosome 18q12-q21 to type 1 diabetes, we evaluated the 12 informative microsatellit...
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