A 63-year-old female with pulmonary hypertension presented to the emergency department (ED) with hemoptysis. Vital signs were significant for tachypnea, with respirations of 30 per minute, and hypoxia, with an oxygen saturation of 88%. Physical examination revealed a systolic cardiac murmur. Bedside emergency ultrasound (EUS) demonstrated a right ventricle that appeared to be enlarged in relati...

T HE CLASSICAL subclavian-pulinonaryt and aortic-pulmonary2 anastomoses were devised as palliative surgical maneuvers for the tetralogy of Fallot complex to augment pulmonary blood flow and to increase systemic arterial saturation. These shunt procedures, performed during the past 14 years, have provided reasonably good health to thousands of patients with severe cyanosis and physical limitatio...

Pulmonary hypertension (PH) results in significant morbidity and mortality. Chronic PH animal models may advance the study of PH's mechanisms, evolution, and therapy. In this report, we describe the challenges and successes in developing three models of chronic PH in large animals: two models (one canine and one swine) utilized repeated infusions of ceramic microspheres into the pulmonary vascu...

Paradoxical embolism is defined as a systemic arterial embolism requiring the passage of a venous thrombus into the arterial circulatory system through a right-to-left shunt. It is a relatively rare phenomenon, representing about 2% of all cases of arterial embolism. We report a case of a 79-years-old woman admitted to hospital because of dyspnea and lower left limb pain. CT scan revealed multi...

perlipidaemic with a positive family history for coronary artery disease (father) and diabetes mellitus (mother) was investigated for chest pain. The clinical examination gave no clear pathological findings. The ECG was normal. Blood biochemistry confirmed the reported hyperlipidaemia. The transthoracic echocardiogram showed a small dilatation of the right cardiac cavities. There was no atrial ...

T HE CLASSICAL subclavian-pulinonaryt and aortic-pulmonary2 anastomoses were devised as palliative surgical maneuvers for the tetralogy of Fallot complex to augment pulmonary blood flow and to increase systemic arterial saturation. These shunt procedures, performed during the past 14 years, have provided reasonably good health to thousands of patients with severe cyanosis and physical limitatio...

A 14-year-old boy with a history of congenital cardiopathy is presented. At age 4, a left systemic-to-pulmonary fistula was performed, using a tubular prosthesis to anastomose the left subclavian artery to the left pulmonary artery. Following this procedure, he developed recurrent episodes of hemoptysis, cough, and left upper lobe consolidation. Treatment resulted in clinical but no radiologic ...

We studied the effect on the circulation of the catecholamines isoproterenol, dopamine, and dobutamine in chronically instrumented lambs with aortopulmonary left-to-right shunts (ages 11 to 87 days) and without shunts (ages 8 to 97 days). Infusion of 0.1 ,ug/kg/min isoproterenol or 10 gvg/kg/min dobutamine markedly increased heart rate and systemic and pulmonary blood flows, while stroke volume...