نتایج جستجو برای: streptozotocin induced diabetes

تعداد نتایج: 1247110  

Journal: :Photochemical and Photobiological Sciences 2021

There is no effective treatment to halt peripheral nervous system damage in diabetic neuropathy. Mitochondria have been at the center of discussions as important factors development neuropathy diabetes. Photobiomodulation has gaining clinical acceptance it shows beneficial effects on a variety disorders. In this study, photobiomodulation (904 nm, 45 mW, 6.23 J/cm2, 0.13 cm2, 60 ns pulsed time) ...

Journal: :Indian journal of physiology and pharmacology 2015
Mousa-Al-Reza Hadjzadeh Ziba Rajaei Reyhaneh Moradi Ahmad Ghorbani

OBJECTIVE Hyperlipidemia is a known complication of diabetes mellitus and predisposes to coronary heart disease. The lowering of total cholesterol and low density lipoprotein (LDL)-cholesterol should reduce the incidence of coronary disease. The aim of the present study was to examine the antihyperlipidemic and antidiabetic effects of the hydroalcoholic extract of watercress (Nasturtium officin...

Journal: :Diabetes 2007
Eric P Davidson Travis L Kleinschmidt Christine L Oltman Donald D Lund Mark A Yorek

In epineurial arterioles, acetylcholine-mediated vascular relaxation is mediated by nitric oxide and endothelium-derived hyperpolarizing factor (EDHF), and both mechanisms are impaired by diabetes. The mediator responsible for the effect of EDHF is unknown. In epineurial arterioles, C-type natriuretic peptide (CNP) has properties consistent with EDHF-like activity. Epineurial arterioles express...

2011
Ramachandran Vadivelan Muthureddy Nataraj Satishkumar Shanish Antony Kannan Elango

The potential role of the ethanolic extract of Asparagus racemosus (Wild) in the treatment of diabetes along with its antioxidant and antihyperlipidemic effects was studied in streptozotocin induced diabetic rats. Oral administration of ethanolic extract of Asparagus racemosus (EEAR) 200 and 400 mg/kg/b.w for 21 days significantly decreased the blood glucose level, fluid intake and considerably...

2014
Esrafil Mansouri Layasadat Khorsandi Hassan Ali Abedi

OBJECTIVES Diabetes plays an important role in the induction of the liver injury. Grape seed proanthocyanidin (GSP) have a wide range of medicinal properties against oxidative stress. In this study we evaluated antioxidant effects of GSP on liver in streptozotocin-induced diabetic rats. MATERIALS AND METHODS Thirty male Sprague-Dawley rats were divided into three groups: control, untreated di...

Journal: :iranian journal of pharmaceutical sciences 0
amir farshchi department of physiology, school of medicine, kermanshah university of medical sciences, kermanshah, iran department of pharmacoeconomics and pharmaceutical management, school of pharmacy, tehran university of medical sciences, tehran, iran golbarg ghiasi department of physiology, school of medicine, kermanshah university of medical sciences, kermanshah, iran department of pharmacoeconomics and pharmaceutical management, school of pharmacy, tehran university of medical sciences, tehran, iran samira ghiasi department of environment, faculty of environmental sciences, islamic azad university, arak branch, arak, iran

diabetes mellitus is associated with disturbances of learning and memory and cognitive functioning. aegle marmelos corr. from rutaceae family, is widely used in iranian folk medicine for the treatment of diabetes mellitus. it decreases blood glucose level by improving glucose tolerance and also has lipid-lowering and antioxidant properties. considering the beneficial antidiabetic potential of a...

2014
Ganapathi Narasimhulu

Herbal therapies are commonly used to treat or manage various diseases including diabetes mellitus. Pimpinella tirupatiensis is Indian traditional medicine and the plant has been a popular remedy for various diseases such as antitumor genic, antimicrobial, purgative, analgesic, antiseptic, antipyretic and anti-inflammatory. The current study was intended to evaluate the antidiabetic efficacy of...

2013
Duraisamy Gomathi Ganesan Ravikumar Manokaran Kalaiselvi Kanakasabapathi Devaki Chandrasekar Uma

AIM Diabetes mellitus (DM), a leading non communicable disease with multiple etiologies is considered as third greatest cause of death in all over the world. During DM, persistent hyperglycemia causes an increased production of free radicals via auto oxidation of glucose and non-enzymatic protein glycation which may lead to disruption of cellular functions and oxidative damage to membranes. The...

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