نتایج جستجو برای: steroid induced atrophy

تعداد نتایج: 1050109  

Introduction:  The aim of this study was to compare the preventive effects of corticosteroids and curcumin on subglottic stenosis in an animal model.  Materials and Methods: Twenty-one male German Shepherd dogs were used for this study. After standardized trauma to the subglottic area, the dogs were divided into three groups. Group A received curcumin (450 mg/ day) for 15 days; Group B received...

Journal: :Japanese Journal of Pharmacology 1980

Journal: :American journal of physiology. Cell physiology 2009
J M McClung A R Judge E E Talbert S K Powers

Recent reports suggest numerous roles for cysteine proteases in the progression of skeletal muscle atrophy due to disuse or disease. Nonetheless, a specific requirement for these proteases in the progression of skeletal muscle atrophy has not been demonstrated. Therefore, this investigation determined whether calpains or caspase-3 is required for oxidant-induced C2C12 myotube atrophy. We demons...

Journal: :The Journal of clinical investigation 2013
Paolo E Porporato Nicoletta Filigheddu Simone Reano Michele Ferrara Elia Angelino Viola F Gnocchi Flavia Prodam Giulia Ronchi Sharmila Fagoonee Michele Fornaro Federica Chianale Gianluca Baldanzi Nicola Surico Fabiola Sinigaglia Isabelle Perroteau Roy G Smith Yuxiang Sun Stefano Geuna Andrea Graziani

Cachexia is a wasting syndrome associated with cancer, AIDS, multiple sclerosis, and several other disease states. It is characterized by weight loss, fatigue, loss of appetite, and skeletal muscle atrophy and is associated with poor patient prognosis, making it an important treatment target. Ghrelin is a peptide hormone that stimulates growth hormone (GH) release and positive energy balance th...

2016
Yasuyuki Sakata Tomoyuki Okamoto Kazutaka Oshio Hirohiko Nakamura Hiroshi Iwamoto Kazuyoshi Namba Yasuhiro Takeda Fumiaki Yoshizawa

BACKGROUND Skeletal muscle atrophy is caused by a variety of diseases and conditions. In particular, skeletal muscle atrophy in the elderly contributes to a loss of independence with advanced age and increases the risk of falling. However, the effect of food consumed on a daily basis on skeletal muscle atrophy has been the focus of little research. In this study, the effects of dietary suppleme...

Journal: :Journal of neurology, neurosurgery, and psychiatry 1982
L A Loizou E B Rolfe H Hewazy

A group of 202 patients with suspected, probable or definite multiple sclerosis was studied, using cranial computed tomography (CT). Atrophy alone, or in combination with white-matter and periventricular lucencies, and areas of contrast enhancement, were the main abnormal findings in 52% of patients. Atrophy was detected in 44% of patients, and its frequency and severity correlated with disease...

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