Editor Associate Editors H. Joseph Newton Francis X. Diebold, University of Pennsylvania Department of Statistics Joanne M. Garrett, University of North Carolina Texas A & M University Marcello Pagano, Harvard School of Public Health College Station, Texas 77843 James L. Powell, UC Berkeley and Princeton University 409-845-3142 J. Patrick Royston, Royal Postgraduate Medical School 409-845-3144 ...

Trophoblast is the primary epithelial cell type in the placenta, a transient organ required for proper fetal growth and development. Different trophoblast subtypes are responsible for gas/nutrient exchange (syncytiotrophoblasts, STBs) and invasion and maternal vascular remodeling (extravillous trophoblasts, EVTs). Studies of early human placental development are severely hampered by the lack of...

The leaf spotting diseases in wheat that include Septoria tritici blotch (STB) caused by , Stagonospora nodorum blotch (SNB) caused by , and tan spot (TS) caused by pose challenges to breeding programs in selecting for resistance. A promising approach that could enable selection prior to phenotyping is genomic selection that uses genome-wide markers to estimate breeding values (BVs) for quantit...

BACKGROUND Spontaneous preterm birth (SPB, before 37 gestational weeks) is a major cause of perinatal mortality and morbidity, but its pathogenesis remains unclear. Studies on SPB have been hampered by the limited availability of markers for SPB in predelivery clinical samples that can be easily compared with gestational age-matched normal controls. We hypothesize that SPB involves aberrant pla...

Enterotoxigenic Escherichia coli (ETEC) that were isolated from neonatal pigs and that did not react in preliminary tests for pilus antigen K88 were subjected to additional tests for K88 and for pilus antigens K99 and 987P. Four such isolates produced K88, 9 isolates produced K99, 55 isolates produced 987P, and the remaining 43 isolates produced none of the three pilus antigens (3P(-)). Immunof...

This study was aimed at determining the effect of type 1 diabetes mellitus on bilirubin excretion, and to ascertain the impact of treatment with crude Aloe vera gel on bilirubin excretion. The phyto-constituents and median lethal dose of the plant material were determined before administration. Forty albino wistar rats were randomly assigned into four groups of 10 rats each as follows; control ...

BACKGROUND Postweaning diarrhoea (PWD) in pigs is usually the main infectious problem of large-scale farms and is responsible for significant losses worldwide. The disease is caused mainly by enterotoxigenic E. coli (ETEC) and Shiga-toxin producing E. coli (STEC). In this study a total of 101 E. coli isolated from pigs with PWD in Slovakia were characterized using phenotypic and genotypic metho...

Effective management of wild animal populations relies on an understanding their spatio-temporal distributions. Passive acoustic monitoring (PAM) is a non-invasive method to investigate the distribution free-ranging species that reliably produce sound. Critically endangered Antarctic blue whales ( Balaenoptera musculus intermedia ) (ABWs) co-occur with pygmy B. m. brevicauda (PBWs) around New Z...

This in vitro study aimed to evaluate surface microhardness, roughness, color, gloss and topography of low-cost Brazilian resin composites, compared with an international one. All 120 samples (8mm ø x 2mm height) were prepared divided into 5 groups: Ultrafill (Biodinâmica), Llis (FGM), Fill Magic (Coltene), Applic (Makira), Filtek Z250XT (3M Oral Care). Surface microhardness (KHN) (n=10) was an...