Overall liquid side volumetric mass transfer coefficient kLa was determined experimentally for cocurrent Taylor flow moving upwards in a glass tube of an internal diameter of 3mm. Experiments were performed for physical absorption of oxygen in 20% aqueous solution of ethanol. Shadowgraph technique was deployed for precise measurements of bubble lengths and velocities. Experimental values of vol...

Angiopoietin-like protein 1 (ANGPTL1) is a potent regulator of angiogenesis. Growing evidence suggests that ANGPTL family proteins not only target endothelial cells but also affect tumor cell behavior. In a screen of 102 patients with lung cancer, we found that ANGPTL1 expression was inversely correlated with invasion, lymph node metastasis, and poor clinical outcomes. ANGPTL1 suppressed the mi...

Recent studies have shown that high miR-155 expression was associated with poor prognosis in patients with acute myelogeneous leukemia (AML). Furthermore, targeting miR-155 results in monocytic differentiation and apoptosis. However, the exact role and mechanisms of miR-155 in human AML remains speculative. HL-60 cells were treated with anti-miR-155 for 72 h. Cell growth and apoptosis in vitro ...

Coupled discrete particle/continuum simulations of the normal (zero obliquity) impact of granular slugs against the centre of deformable, end-clamped beams are reported. The simulations analyse the experiments of Uth et al. (2015) enabling a detailed interpretation of their observations of temporal evolution of granular slug and a strong stand-off distance dependence of the structural response....

This study uses high-speed imaging to characterize microchannel slug flow boiling using a novel experimental test facility that generates an archetypal flow regime suitable for highfidelity characterization of key hydrodynamic and heat transfer parameters. Vapor and liquid phases of the fluorinated dielectric fluid HFE-7100 are independently injected into a T-junction to create a saturated two-...

n ABSTRACT This paper presents a theoretical investigation of the movement of liquid droplets and slugs in hydrophobic microchannels and develops a compact model for this type of two-phase flow. This model is used in the prediction of pressure drop and liquid water coverage ratio, key parameters in the operation of Proton Exchange Membrane Fuel Cells (PEMFC), the primary motivation for this wor...

Motive forces of migrating pseudoplasmodia (slugs) of Dictyostelium discoideum were determined by application of a double-chamber method. The motive force of a whole slug was proportional to its volume, the value per unit volume being 5.85 x 10(-6) dyne/cm3 (58.5 N cm-3). The motive force was independent of temperature (13.5--26 degrees C) and decreased during prolonged migration. Motive force ...

Despite extensive investigation, the precise contribution of the ultraviolet radiation (UVR) component of sunlight to melanoma etiology remains unclear. UVR induces keratinocytes to secrete proinflammatory and immunomodulatory mediators that promote inflammation and skin tumor development; expression of the slug transcription factor in keratinocytes is required for maximal production of these m...

Epichloë typhina, a fungal endophyte of cool season grasses, is heterothallic and an obligate out-crosser. In areas of endemism, its spermatia are moved between stromata of the two opposite mating types through egg-laying activities of Botanophila flies. In western Oregon, where the fungus was inadvertently introduced into seed-production fields of Dactylis glomerata (= orchardgrass, cocksfoot)...

The transcription factors Snail, Slug and Twist repress E-cadherin and induce epithelial-mesenchymal transition (EMT), a process exploited by invasive cancer cells. In this study, we evaluated the role of EMT in the tumorgenesis of neuroendocrine tumors of the pancreas (PNETs) in vitro, in vivo and human tumor specimen. Expression of EMT markers was analyzed using immunohistochemistry and real-...