The reliability of immunological identification of Neisseria gonorrhoeae using polyclonal and monoclonal antibody coagglutination reagents has been evaluated. When clinical isolates of neisseriae were tested in an "in use" trial the sensitivity and specificity of each reagent were similar and the overall agreement with carbohydrate utilisation was 97.9% (141/144) for the polyclonal antibody rea...

BACKGROUND In 2009, we investigated the conformance of 8 hemoglobin A(1c) (Hb A(1c)) point-of-care (POC) instruments. Since then, instruments have improved and new devices are available on the market. In this second study, we evaluated the performance of DCA Vantage, Afinion, InnovaStar, Quo-Lab, Quo-Test, Cobas B101, and B-analyst Hb A(1c) POC instruments. METHODS Clinical and Laboratory Sta...

Etoposide is an effective anticancer agent whose antitumor activity is associated with its phenolic E-ring, which can participate in intracellular redox cycling reactions. Myeloperoxidase (MPO)-catalyzed one-electron oxidation of the etoposide phenolic ring and/or interaction of this phenolic moiety with reactive radicals yields its phenoxyl radical, whose reactivity may determine the pro- or a...

A novel, simple p-dimethyl amino benzyl ethylene diamine reagent has been synthesized under ordinary laboratory conditions and this reagent was successfully applied for the determination of Chromium (VI) in various environmental samples. This reagent yields a red colored complex with chromium metal solution in sodium acetate-acetic acid buffer of pH 7.0. Maximum absorption was obtained at 560 n...

Fatemeh Karimi Tabar was born in Asadabad/Hamedan (Iran) in 1986. She completed her B.Sc. in chemistry in 2008 from Bu-Ali Sina University, Hamedan, Iran. She was graduated from M.Sc. degree in organic chemistry from Shiraz University 2010, Shiraz, Iran. She is currently Organic Chemistry Ph.D student under the supervision of prof. M.A. Zolfigol and prof. A. Khazaei in department of chemistry a...

This chemical sensor method was selected to detect cyanide in this paper. We synthesized a new reagent which can produce color change from colorless to yellow when encountering cyanide. According to this feature, this reagent can be used to identify cyanide. This reagent had also a good ability of anti-interference, the color change is not obvious when this reagent Encounter the interference io...

A solid-phase reagent for determination of urinary specific gravity (relative density) is described. This reagent strip, similar to others in the "N-Multistix" series (Ames), contains a polyacid whose acidity is sensitive to the ionic concentration in the urine in which it is immersed. As the acidity of the polyacid changes, pH changes are detected by a pH indicator within the reagent strip. In...

The combination of P4S10 and hexamethyldisiloxane efficiently converts esters, lactones, amides, lactams, and ketones to their corresponding thiono derivatives. In the presence of elemental sulfur, 3-oxoesters are converted to dithiolethiones by this reagent. Yields are comparable to or superior to those obtained with Lawesson's reagent. The method has the advantage that reagent-derived byprodu...

393 primary school children were screened for Schistosoma haematobium using four indirect techniques (a) history of haematuria, (b) visual appearance of urine and use of chemical reagent strips to detect presence of (c) blood and (d) protein in urine. Results showed that the use of chemical reagent strips for the detection of blood was the most specific and sensitive method, even in areas of lo...

OBJECTIVES To evaluate the effect of storing commonly used rapid diagnostic tests above manufacturer-recommended temperature (at 37°C), and the accuracy of delayed reading of oral fluid kits with relevance to HIV self-testing programmes. DESIGN A quality assurance study of OraQuick (OraSure), Determine HIV 1/2™ (Alere) and Uni-Gold™ (Recombigen®). METHODS Consecutive adults (≥18y) attending...