Objective: To determine the regenerating effect of hyaluronic acid on circumferential bone defects in albino Wistar rats. Material and Methods: An experimental type study was designed carried out with 15 male rats, 4 months old weighing between 250 350 grams. Two 3mm diameter 0.8mm deep were created calvaria parietal (on both sides midline). One defect filled a demineralized matrix (control gro...

Background: Individually, green tea and coffee have been extensively studied for mitigation of metabolic syndrome (MS) in both rats humans; however, their combined effect requires further investigation. Thus, we compared the combining decaffeinated light roasted on MS rats. Methods: An animal model was constructed by feeding Spragu...

Continuously performing heavy activities will damage tissues and cells cause oxidative stress. Fortunately, this can be reduced by giving antioxidants to reduce free radicals. This study uses the forced swimming test model determine effect of Javanese ginseng root extract on superoxide dismutase levels in male white Sprague Dawley rats. The samples were 30 rats divided into five groups: negativ...

Purpose: To investigate the effect of quaternary amines on myocardial cells a rat model cardiac arrest, with respect to energy generation potential and oxygen free radicals.
 Methods: Forty-five Sprague-Dawley (SD) rats were assigned sham, amine groups (each 15 rats). After their corresponding treatments, lectrocardiogram (ECG) monitoring in three at various time periods was carried out. S...

Melatonin has diverse effects, and been reported to promote bone formation in addition regulating the sleep–wake cycle. In present study, we investigated effects of melatonin on metabolism using ovariectomized (OVX) rats; a model postmenopausal osteoporosis. Here, focused differences when was subcutaneous injected at day or early night. The OVX rats were with once daily (0.8 8 mg/head) between ...

Purpose The ketogenic diet (KD) has gained popularity due to its ability improve type 2 diabetes, weight loss, antioxidant and anti-inflammatory activity. However, long-term use of the KD might not be safe adverse effects. This study examined effects alone or in combination with Zamzam water (holy for Muslims) on glucose homeostasis, lipid parameters oxidant-antioxidant variables rats. Design/m...

Hypertension of SHR appears at an early age and progressively increases. This study aimed to evaluate the effect lycopene in with mild hypertension (young rats) or high level (adult rats). Four-weeks treatment 10 mg/kg/day decreased blood pressure young (from 144 ± 2 119 3 mmHg) adult 177 5 159 7 SHR. Heart renal hypertrophy fibrosis were increased compared lycopene, regardless rats, improved i...

Cardiovascular effects of LVV-hemorphin-7, a member of the family of fragments from beta-chain of human or bovine hemoglobin, were studied in conscious spontaneously hypertensive (SHR) and Wistar-Kyoto (WKY) rats by radiotelemetry. Intraperitoneal injection of hemorphin in a dose of 100 microg/kg significantly decreased blood pressure in SHR, whereas negligible effect was seen in normotensive W...

This study aims to evaluate the impact of adding different items in individually ventilated rat cages on the animal's activity, cardiovascular parameters and faecal stress indicators. The following three cage items made of aspen were compared: a cross made of two intersecting boards, a similar cross where drilled holes were loaded with food pellets (restricted feeding) and a rectangular tube. M...

Histocompatible Fischer 344 and Lewis rats have been shown to differ on a wide variety of behavioral, chemical, and molecular measures. This investigation aimed to clarify strain differences in unconditioned motor behavior with respect to the amount and patterns of movements. Twenty female Fischer 344, Lewis, and Sprague-Dawley were tested in the Behavioral Pattern Monitor for 30 min. The locom...