OBJECTIVES Solid dispersion formulation is the most promising strategy to improve oral bioavailability of poorly water soluble drugs. The aim of this study was to compare the effect of polyvinylpyrrolidone K30 (PVP) and poloxamer-188 (PLX) as carrier in solid dispersion formulations of celecoxib (CLX). MATERIALS AND METHODS Solid dispersions of CLX:PVP or CLX:PLX were prepared at different ra...

PURPOSE There is little data evaluating the changes of severity of bladder outlet obstruction after 80 W-potassium-titanyl-phosphate (KTP) photoselective laser vaporization prostatectomy (PVP) by pressure-flow study. We evaluated the efficacy of PVP to relieve the obstruction in benign prostate hyperplasia (BPH) compared with transurethral resection of the prostate (TURP). MATERIALS AND METHO...

BACKGROUND AND OBJECTIVE The existing literature is inconsistent regarding whether there is any additional effect of povidone-iodine (PVP-iodine) as an adjunctive to scaling and root planing, and, if there is an effect, what its size is. Therefore, the aim of this study was to assess the additional effect of PVP-iodine as an adjunct to scaling and root planing compared with water, saline or no ...

In the present study, polyvinylpyrrolidone films containing amino acid-based surfactant, namely, sodium lauroyl sarcosinate (SLS), were prepared by casting method. The obtained (PVP/SLS) characterized means of attenuated total reflectance-Fourier transform infrared spectroscopy (ATR-FTIR), optical properties, thermogravimetric analysis (TGA), differential scanning calorimetry (DSC) and moisture...

cobalt ferrite (cofe2o4) nanorods were synthesized by iron chloride (fecl3.6h2o) and cobalt sulfate hexahydrate (coso4.7h2o) as precursor in the presence of ethylene glycol agent and poly vinyl pyrrolidone (pvp) surfactant. the samples were characterized to identify the physical properties. xrd pattern of cobalt ferrite samples showed the structure of body center cubic (bcc) structure. the diam...

The aim of this study is to investigate the effect graphite (GR) content on morphology and wettability polyvinylpyrrolidone (PVP) / GR composite nanofibers. For purpose, PVP PVP/GR nanofiber mats various filler contents (0.6%, 1.2%, 1.8%, 2.4%, 3%, 3.6% 4.2 % (wt.% PVP)) were fabricated by electrospinning. diameters nanofibers characterized SEM. Average 218 nm for unfilled between 170 203 obser...

objective(s): three-dimensional structures such as nanofibrous scaffolds are being used in biomedical engineering as well as provide a site for cells to attach and proliferate leading to tissue formation. in the present study, poly(vinyl pyrrolidone) (pvp)/ poly(vinyl alcohol)(pva) hybrid nanofibrous scaffold was synthesized by electrospinning. materials and methods: the effect of adding nano h...

Recurrence at the site of a stapled anastomosis is generally believed to result from the luminal implantation of viable cancer cells during stapling. We report a case in which colon cancer recurred twice at the site of a stapled anastomosis, despite povidone iodine (PVP-I) lavage consisting of an enema with 5% PVP-I solution before the operation and intraoperative lavage of the rectal remnant a...

The nanocomposite polyvinyl pyrrolidone (PVP) films containing Ag nanoparticles and Rhodamine 6G are prepared on the two-dimensional distinctive continuous ultrathin gold nanofilms. We investigate the optical properties and the fluorescence properties of silver nanoparticles-PVP polymer composite films influenced by Ag nanoparticles and Au nanoparticles. Absorption spectral analysis suggests th...

□ The medicated hydrogels were prepared aseptically under moist heat treatment using polyvinylpyrrolidone (PVP), sodium-carboxymethylcellulose (CMC), polyethyleneglycol (PEG), agar, glycerin and/or boric acid (BA) and designated as PVP-CMC and PVP-CMC-BA. The aim of this study was to develop some medicinal values-based hydrogels. BA was used to build up the medicinal values (antiseptic and anti...