Putrescine plays a distinct role in various types of biological functions all living organisms, as well environmental stress. The aim the study is to effect exogenous putrescine on physiological condition rice seeds investigated. Salt treatment resulted reduction speed germination, germination energy, energy percentage, final shoot and root length, plant dry weight, where proline content was re...

We have generated a hybrid transgenic mouse line overexpressing both ornithine decarboxylase (ODC) and spermidine/spermine N(1)-acetyltransferase (SSAT) under the control of the mouse metallothionein (MT) I promoter. In comparison with singly transgenic animals overexpressing SSAT, the doubly transgenic mice unexpectedly displayed much more striking signs of activated polyamine catabolism, as e...

Putrescine was first isolated from putrifying meat and was thought of as a decomposition product; spermine was named from its occurrence in semen. These polyamines, however, are now known to have important roles in cell growth and differentiation. Their physiological significance can be studied by analyzing the consequences of depletion of the cellular polyamine content. The results include arr...

Plants activate antioxidant defense mechanisms under stress, which help maintaining the structural integrity of cell components and possibly reduces oxidative damage.  Low temperature stress leads to the production of reactive oxygen species and oxidative damage to plants. In this study, the effect of putrescine and proline on reducing the production of reactive oxygen species and increasing th...

Biogenic amines (BAs) are low molecular weight nitrogenous organic compounds with different biological activities. Putrescine, spermidine and spermine are essential for the development of the gut and immune system of newborns, and are all found in human milk. Little is known, however, about the role of histamine, tyramine or cadaverine in breast milk. Nor is it known whether mastitis alters the...

Putrescine can be converted to y-aminobutyraldehyde by enzymes from different sources (l-3). It. is generally believed that this conversion is catalyzed by a nonspecific diamine oxidase. The presence of such an enzyme in bacteria, however, has not been firmly established experimentally. We have previously reported that, in a mutant of Escherichia co& B selected to grow on putrescine as the sole...

The incorporation of l-[(14)C]ornithine and [(14)C]putrescine into putrescine, spermidine, and spermine in type 5 adenovirus-infected KB cells was identical to that in uninfected control cells early in infection, but incorporation into putrescine stopped after 8 to 12 h and the rate of incorporation into spermidine was reduced between 12 and 20 h after infection. The amount of polyamines found ...

Polyamines are polycationic molecules essential for cell growth and differentiation. Recent work has focused on cell polyamine-transport systems as a way to regulate intracellular polyamine levels. In this study, we demonstrate the presence of two different active transporters for putrescine and spermidine in a rat tumoral cell line (AR4-2J). The first has a Km of 3.1 microM and a Vmax of 3.7 p...

A series of diamine homologues of putrescine and triamine homologues of spermidine was used to determine the structural specificity of the polyamine transport system in asertes L1210 leukemia cells by measuring their ability to compete with [3H]putrescine, [3H]spermidine, or [3H]spermine for uptake. Trans port specificity among the diamines (as indicated by K,constants) was greatest for those h...