Lysophosphatidylcholine (lyso-PC), a natural lipid generated through the action of phospholipase A2 on membrane phosphatidylcholine, has been implicated in atherogenesis and the inflammatory process. In vitro studies have established a role for lyso-PC in modulation of gene expression and other cellular responses including differentiation and proliferation. There is also evidence that lyso-PC m...

Our study was aimed at exploring the roles of lncRNA RP11-400K9.4 (RP11-400K9.4) on hypoxia/reoxygenation (H/R) -induced cardiomyocytes apoptosis. H/R model constructed in rat primary (PC) and H9c2 cells. In this study, results showed that significantly induced apoptosis PC The expression upregulated H/R-induced cells, but miR-423 downregulated. Silencing could attenuate We also found a potenti...

The role of stress-activated protein kinases (SAPKs), c-Jun NH(2)-terminal kinase (JNK) and p38 mitogen-activated protein (MAP) kinase, in preconditioning (PC) was examined with the use of isolated rat hearts subjected to four cyclic episodes of 5-min ischemia and 10-min reperfusion followed by 30-min ischemia and 2-h reperfusion (I/R). A group of hearts was preperfused with 100 microM curcumin...

Okumura, Manabu, Hirofumi Kai, Shinya Shinozawa, Yoichiro Isohama, and Takeshi Miyata. Effects of eosinophil granule major basic protein on phosphatidylcholine secretion in rat type II pneumocytes. Am. J. Physiol. 276 (Lung Cell. Mol. Physiol. 20): L763–L768, 1999.—Eosinophils are involved in inflammatory diseases such as asthma. We previously reported that activated eosinophils increased the p...

Recently that the contents get various due to spread of prosumer and contents can be shared with others due to appearance of SNS, the private internet broadcasting services become activated gradually. For this reason, they were used to the editorial broadcasting base virtual studio system to support more high quality broadcasting than traditional methods like real-time personal broadcasting usi...

Acrylonitrile butadiene styrene (ABS) and polycarbonate (PC) are considered a well-known class of engineering thermoplastics due to their efficient use in automotive, 3D printing, electronics. However, improvement toughness, processability, thermal stability is achieved by mixing together ABS PC. The present study focuses on the understanding surface mechanical characterization acrylonitrile bl...

We previously reported the tumor-suppressive activity of insulin-like growth factor binding protein-related protein 1 (IGFBP-rP1) through induction of apoptosis in human prostate cancer cells. The aim of this study was to investigate the effects of IGFBP-rP1 for radiosensitivity and chemosensitivity in hormone-refractory human prostate PC-3 cancer cells. Five assays were performed using PC-3 ce...

BACKGROUND & AIMS Defects in Paneth cell (PC) function are associated with microbial dysbiosis and intestinal inflammation. PC granules contain antimicrobial peptides, cytokines, and substantial stores of zinc (Zn). We hypothesized that Zn, transported into the granule through the Zn transporter (ZnT)2, is critical for signature PC functions. METHODS ZnT2 was localized to PC granules using im...

castor bean, peanut, soy bean and safflower protein isolates were prepared. the amino acid content of each of the protein isolates was analysed and the essential amino acid contents were compared with the fao human requirements. the results indicated that castor bean has the highest oil and the protein content of defatted meal. safflower 3148 (marand, iran) has the highest amount of essential a...