نتایج جستجو برای: prevalent cancers

تعداد نتایج: 159263  

Journal: :Clinical journal of oncology nursing 2011
Catherine M Jankowski Ellyn E Matthews

Cancer survivors face many challenges as a result of their cancer diagnosis and treatment, most importantly the maintenance of physical well-being. Nurses and other health professionals strive to address the needs of cancer survivors, including providing appropriate health-promotion information for a physically active lifestyle. Cancer survivors are at greater risk for recurrence and for develo...

Journal: :Kompass 2023

The number of new cases cancer is increasing each year, and rates diabetes mellitus are also dramatically over time. It not an unusual occurrence for individual to have both at the same time, given they individually common, that one condition can increase risk other. In this manuscript, we use national-level (Virtual Diabetes Register) (New Zealand Cancer Registry) data on nearly five million i...

Journal: :Molecular cancer therapeutics 2015
Yoshihiro Joshua Ono Akiko Tanabe Tomohito Tanaka Yoshimichi Tanaka Masami Hayashi Yoshito Terai Masahide Ohmichi

Endometrial cancer is the most prevalent gynecologic cancer in the Western world, and the number of advanced chemotherapy-resistant cancers is increasing with the absolute increase in patients. The development of resistance to chemotherapeutic drugs by cancer cells represents a major challenge in the clinical cure of advanced and metastatic cancers. CD24 has been reported to be a marker for a p...

Journal: :Annual review of pathology 2009
Yong Sun Lee Anindya Dutta

Within the past few years, studies on microRNA (miRNA) and cancer have burst onto the scene. Profiling of the miRNome (global miRNA expression levels) has become prevalent, and abundant miRNome data are currently available for various cancers. The pattern of miRNA expression can be correlated with cancer type, stage, and other clinical variables, so miRNA profiling can be used as a tool for can...

2011
Takashi Oka Hiaki Sato Mamoru Ouchida Atae Utsunomiya Tadashi Yoshino

Although cancers have been thought to be predominantly driven by acquired genetic changes, it is becoming clear that microenvironment-mediated epigenetic alterations play important roles. Aberrant promoter hypermethylation is a prevalent phenomenon in human cancers as well as malignant lymphoma/leukemia. Tumor suppressor genes become frequent targets of aberrant hypermethylation in the course o...

Journal: :Best practice & research. Clinical obstetrics & gynaecology 2006
R Sankaranarayanan J Ferlay

The estimation of cancer burden is valuable to set up priorities for disease control. The comprehensive global cancer statistics from the International Agency for Research on Cancer indicate that gynaecological cancers accounted for 19% of the 5.1 million estimated new cancer cases, 2.9 million cancer deaths and 13 million 5-year prevalent cancer cases among women in the world in 2002. Cervical...

2017
Michael X. Ma Michael J. Bourke

Serrated polyps are important contributors to the burden of colorectal cancers (CRC). These lesions were once considered to have no malignant potential, but currently up to 30% of all CRC are recognized to arise from the serrated neoplasia pathway. The primary premalignant lesions are sessile serrated adenomas/polyps (SSA/Ps), although traditional serrated adenomas are relatively uncommon. Comp...

Journal: :Cell 2009
Ji Luo Michael J. Emanuele Danan Li Chad J. Creighton Michael R. Schlabach Thomas F. Westbrook Kwok-Kin Wong Stephen J. Elledge

Oncogenic mutations in the small GTPase Ras are highly prevalent in cancer, but an understanding of the vulnerabilities of these cancers is lacking. We undertook a genome-wide RNAi screen to identify synthetic lethal interactions with the KRAS oncogene. We discovered a diverse set of proteins whose depletion selectively impaired the viability of Ras mutant cells. Among these we observed a stron...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2015
Abhik Saha Hem C Jha Santosh K Upadhyay Erle S Robertson

DNA-methylation at CpG islands is one of the prevalent epigenetic alterations regulating gene-expression patterns in mammalian cells. Hypo- or hypermethylation-mediated oncogene activation, or tumor suppressor gene (TSG) silencing mechanisms, widely contribute to the development of multiple human cancers. Furthermore, oncogenic viruses, including Epstein-Barr virus (EBV)-associated human cancer...

Journal: :Nephrology Dialysis Transplantation 2021

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