This study was performed to achieve sustained-release Ibuprofen matrix tablets with a zero-order release kinetic while most of the previous formulations have shown Higuchi release kinetic. Considering the results from previous studies, ethyl cellulose, Carbopol 934P, Carbopol 974P, and Pemulen TR-1 were used at different amounts for preparation of the tablets by direct compression. The release ...

Enzymes that hydrolyze extracellular ATP, i.e. ecto-ATPase and ecto-ATP diphosphohydrolase (ATPDase), can be differentiated by ability of the latter to hydrolyze ADP and by slightly different kinetic properties of the two enzymes. Synaptic plasma membrane fractions isolated from rat hippocampus and caudate nucleus exhibit ADP-hydrolyzing activity, as revealed by the enzyme assay, and the presen...

The most natural kinetic data structure for maintaining the maximum of a collection of continuously changing numbers is the kinetic heap. Basch, Guibas, and Ramkumar proved that the maximum number of events processed by a kinetic heap with n numbers changing as linear functions of time is O(n log n) and Ω(n log n). We prove that this number is actually Θ(n log n). In the kinetic heap, a linear ...

OBJECTIVE This study assessed the muscular activity during root canal preparation through kinematics, kinetics, and electromyography (EMG). MATERIAL AND METHODS The operators prepared one canal with RaCe rotary instruments and another with Flexo-files. The kinematics of the major joints was reconstructed using an optoelectronic system and electromyographic responses of the flexor carpi radial...