We recently reported that activation of the highly efficient phospholipase C (PLC) stimulatory m3 muscarinic acetylcholine receptor (mAChR) can induce a long-lasting Gi-mediated heterologous potentiation of PLC stimulation in human embryonic kidney (HEK) 293 cells, which was accompanied by an increased cellular level of the PLC substrate phosphatidylinositol-4,5-bisphosphate [PtdIns(4,5)P2]. He...

in this article, a speed control of dc motor is designed and illustrated using fuzzy logic-based programmable logic controller (plc). the dc motor is an attractive part of electrical equipment in many industrial applications requiring variable speed and load specifications due to its ease of controllability. the designed system is consisted of three main parts including programmable logic contr...

Formal methods for real-time systems are an important topic of contemporary research. The aim is to cope with the additional complexity of \time" in speciication and veriication. In Die99a] we present an approach to the correct design of real-time programs implemented on \Programmable Logic Controllers" (PLCs). This hardware executes repeatedly an application program whereas each cycle has an u...

Propionyl-l-carnitine (PLC) is a natural short-chain derivative of l-carnitine (LC), a natural amino acid that plays an important role in fatty acid metabolism. Recent studies suggest that PLC has vascular protective effects. Because of the importance of endothelial nitric oxide synthase (eNOS) and its product, antiatherogenic molecule nitric oxide (NO), in vascular endothelial function, we sou...

Broadband PLC systems, achieving data rates beyond 2 Mbps, which are applied to the low-voltage power supply networks to build up so-called PLC access networks, suppose to use a frequency spectrum up to 30MHz. However, the supply networks are not designed for communications and they act as antennas, producing electromagnetic radiation and causing disturbances to other telecommunications service...

selection of appropriate strategies is one of the important principles to achieve profitability in the business models. one of the most important of these strategies, is use of appropriate pricing strategies in order to have the correct and satisfy product pricing process, the factors that affect pricing should be identify and control. plc as organizational factors affecting group is of the mai...

It is unknown whether loss in musculotendinous tissue during inactivity can be counteracted by growth hormone (GH), and whether GH accelerate rehabilitation in aging individuals. Elderly men (65-75 yr; n = 12) had one leg immobilized 2 wk followed by 6 wk of retraining and were randomly assigned to daily injections of recombinant GH (rhGH; n = 6) or placebo (Plc; n = 6). Cross-sectional area (C...

Phospholipase C (PLC) was purified to homogeneity from the culture filtrate of Bacillus cereus (65-fold, 540 U/mg protein) and B. thuringiensis (76-fold, 306 U/mg protein) by conventional techniques of enzyme purification. The purified enzymes have the molecular mass of 34 kDa and 38 kDa respectively, as determined by SDS-PAGE. Both the PLCs exhibited identical sensitivity to pH, temperature, c...

Stimulation of the T cell antigen receptor (TCR) activates a protein tyrosine kinase and leads to the tyrosine phosphorylation of phosphoinositide-specific phospholipase C-gamma 1 (PLC gamma 1). The molecular interactions involved in this phosphorylation are not known. After stimulation of the TCR on Jurkat T cells, tyrosine-phosphorylated proteins of 36, 38, 58, and 63 kD coprecipitate with PL...

The 145-kDa phospholipase C isozyme, PLC-gamma, is an excellent substrate for the epidermal growth factor (EGF) receptor both in vivo and in vitro. We now demonstrate that EGF treatment of HSC-1 cells, a human squamous cell carcinoma-derived cell line that expresses high levels of the EGF receptor, rapidly induces tyrosine phosphorylation of two-thirds of the total cellular PLC-gamma pool. A tw...