Physiological roles of endogenous nitric oxide (NO) in the lymphatic pump activity of rat mesenteries in vivo were evaluated using an intravital video microscope system. Changes in the pumping frequency (F), the end diastolic diameter (EDD), and the end systolic diameter (ESD) of the mesenteric lymph microvessels were measured with the microscope system and then the pump flow index (PFI) was ca...

Correspondence During the past 3 years, Dr Chapman has received compensa tion for consulting with AstraZeneca, Boehringer-Ingelheim, CSL Behring, GlaxoSmithKline, Merck Frosst, Novartis, Nycomed, Pfi zer, Roche, Schering Plough, and Telacris; has undertaken research funded by AstraZeneca, Boehringer-Ingelheim, CSL Behring, Forest Laboratories, GlaxoSmithKline, Novartis, Parangenix, Roche, and T...

BACKGROUND A prospective phase II study was conducted to evaluate the efficacy and toxicity of the combination docetaxel (Taxotere) (DTX) and oxaliplatin (OXA) in ovarian cancer patients recurring after a platinum-free interval (PFI) >12 months. PATIENTS AND METHODS DTX, 75 mg/m(2), was administered by 60 min i.v. infusion, followed by OXA, 100 mg/m(2), given by a 2 h i.v., on day 1 every 21 ...

BACKGROUND In humans and rodents obesity appears to promote some cancers by increasing incidence, tumor aggressiveness, recurrence, and fatality. However, the relationship between obesity and cancer in dogs has not been thoroughly evaluated. HYPOTHESIS/OBJECTIVES Whether body condition score (BCS) at the time of lymphoma (LSA) or osteosarcoma (OSA) diagnosis in dogs is predictive of survival ...

BACKGROUND OVA-301 is a large randomized trial that showed superiority of trabectedin plus pegylated liposomal doxorubicin (PLD) over PLD alone in relapsed ovarian cancer. The optimal management of patients with partially platinum-sensitive relapse [6-12 months platinum-free interval (PFI)] is unclear. PATIENTS AND METHODS within OVA-301, we therefore now report on the outcomes for the 214 ca...

Gaseous fuels, e.g., natural gas, biogas, have several advantages over liquid fuels owing to their favorable physical and chemical properties, lower carbon numbers in the fuel composition no issues regarding evaporation. The present study investigated compressed gas (CNG) port injection (PFI) direct (DI) systems compared gasoline (GDI) cases a spark ignition (SI) naturally aspirated single cyli...

Interfaces play a crucial role in determining perovskite solar cells, (PSCs) performance and stability. It is therefore of great importance to constantly work toward improving their design. This study shows the advantages using hole-transport material (HTM) that can anchor surface through halogen bonding (XB). A halo-functional HTM (PFI) compared reference (PF), identical optoelectronic propert...

Singapore is one of the most populous countries, and majority population stays in high-rise public flats. In 2021, there were about 1.1 million residential units, which 79% above 20 years old. The number incidents falling objects from a height has been increasing due to aging deterioration buildings. Periodic Façade Inspection (PFI) regime was enacted 2020 mandate façade inspections for all bui...