نتایج جستجو برای: persistent pulmonary hypertension

تعداد نتایج: 438281  

Journal: :The European respiratory journal 2006
R J Hughes X Jais D Bonderman J Suntharalingam M Humbert I Lang G Simonneau J Pepke-Zaba

The treatment of choice for chronic thromboembolic pulmonary hypertension (CTEPH) is pulmonary endarterectomy (PEA). However, many patients develop a severe progressive small vessel pulmonary arteriopathy that is inaccessible to surgical intervention and is associated with poor survival. The purpose of the present study was to evaluate the medium-term efficacy and safety of the dual endothelin ...

2008
Xavier Jaïs Hossein A. Ghofrani Irene M. Lang

Methods The BENEFiT (Bosentan Effects in iNopErable Forms of chronIc Thromboembolic pulmonary hypertension) study was a double-blind, randomized, placebo-controlled study in CTEPH including patients with either inoperable CTEPH or persistent/recurrent pulmonary hypertension after PEA ( 6 months after PEA). Independent coprimary end points were change in PVR as a percentage of baseline and chang...

Journal: :Journal of pediatric surgery 2011
Lefteris Stathopoulos Claire Nicaise Fabrice Michel Laurent Thomachot Thierry Merrot Pierre Lagier Claude Martin

We report the case of a 38-week gestational age neonate, with isolated congenital diaphragmatic hernia presenting with refractory persistent pulmonary hypertension, systemic hypotension, and hypoxemia, resistant to usual therapeutics. Arginine vasopressin is responsible for systemic vasoconstriction and decreases pulmonary hypertension. We theorized that terlipressin, its long-acting analogue, ...

Journal: :Archives of disease in childhood 1998
S G Haworth

This is an opportune time to reappraise primary pulmonary hypertension. The disease is still incurable but recent laboratory studies are beginning to provide clues to its pathogenesis, and we now know that survival is improved by sustained intravenous prostacyclin treatment and by chronic anticoagulation. In 1991, before these treatments were generally available, the median survival was given a...

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