The dynamic strength index (DSI), often calculated as the ratio of countermovement jump (CMJ) propulsion peak force to isometric mid-thigh pull (IMTP) peak force, is said to inform whether ballistic or maximal strength training is warranted for a given athlete. CMJ propulsion peak force is highly influenced by jump strategy, however, which is not highlighted by the DSI alone. This study aimed t...

Exosomes are sub-100 nm extracellular vesicles secreted by normal and cancer cells. We present a high-resolution structure of previously unidentified nanofilaments on glioblastoma-derived exosomes, using nanoscale peak force imaging. These stiff, adhesive, trypsin- and RNAse-resistant surface nanofilaments add a new dimension to the current structural knowledge of exosome-mediated intercellular...

The effect of cell size on the out of plane compressive crushing response of circular cell polycarbonate honeycomb is presented. Over 100 experiments were conducted on specimens ranging in size from 1 to 169 cells (number of cells=N). Experiments showed that for N<19 there was a significant increase in crushing load. The maximum crushing load was observed where N=7. Finite element (FE) analysis...

BACKGROUND Kinesio Taping (KT) is widely used, however the effects of KT on muscle activation and force are contradictory. OBJECTIVE To evaluate the effects of KT on knee extension force in soccer players. METHOD This is a clinical trial study design. Thirty-four subjects performed two maximal isometric voluntary contractions of the lower limbs pre, immediately post, and 24 hours after tape...

Irregularities in force output are present throughout human movement and can impair task performance. We investigated the presence of a large force discontinuity (after-peak reduction, APR) that appeared immediately following peak in maximal effort ramp contractions performed with the thumb adductor and ankle dorsiflexor muscles in 25 young adult participants (76% males, 24% females; M age 24.4...

Excessive contact force is believed to contribute to the development of medial compartment knee osteoarthritis. The external knee adduction moment (KAM) has been identified as a surrogate measure for medial contact force during gait, with an abnormally large peak value being linked to increased pain and rate of disease progression. This study used in vivo gait data collected from a subject with...

REASON FOR PERFORMING STUDY Foals stand and walk immediately after birth, but insight into the subsequent longitudinal development of their gait kinetics in the early juvenile phase and the possible influence of osteochondrosis thereon is lacking. OBJECTIVES To quantify gait kinetics in foals during the first half year of life, taking into account their osteochondrosis status. STUDY DESIGN ...

Experiments were performed in human working myocardium to investigate the relationship of intracellular calcium handling and availability to alterations in the strength of contraction produced by changes in stimulation rate and pattern. Both control and myopathic muscles exhibited potentiation of peak isometric force during the postextrasystolic contraction which was associated with an increase...

Force platforms are used extensively to measure force and power output during countermovement jump (CMJ). The purpose of this study was to examine measurement reliability and validity of commonly used performance measurements derived from ground reaction force (GRF)-time data during CMJ and the influence of sampling at different frequencies. Twenty-four men performed 2 trials of CMJ on a force ...